Evidence map›Paper›PMID 28890698›Full record

ArticleFrontiers in pharmacology2017

Multi-Target Screening and Experimental Validation of Natural Products from

Yin-Hua Deng, Ning-Ning Wang, Zhen-Xing Zou, Lin Zhang, Kang-Ping Xu, Alex F Chen, Dong-Sheng Cao, Gui-Shan Tan

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Trilobatin Protects Against AβFrontiers in pharmacology · 2020
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yin-Hua DengXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Ning-Ning WangXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Zhen-Xing ZouXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Lin ZhangCollege of Food Science and Technology, Central South University of Forestry and TechnologyChangsha, China.
Kang-Ping XuXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Alex F ChenXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Dong-Sheng CaoXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.
Gui-Shan TanXiangya School of Pharmaceutical Sciences, Central South UniversityChangsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder which is considered to be the most common cause of dementia. It has a greater impact not only on the learning and memory disturbances but also on social and economy. Currently, there are mainly single-target drugs for AD treatment but the complexity and multiple etiologies of AD make them difficult to obtain desirable therapeutic effects. Therefore, the choice of multi-target drugs will be a potential effective strategy inAD treatment. To find multi-target active ingredients for AD treatment from

Indexed as

AlzheimerBACE1MAO-Bmulti-target SARmulti-target screeningSelaginella plants

Identifiers

PMID28890698
PMCPMC5574911

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.