Evidence map›Paper›PMID 28890521›Full record

ArticleThe Journal of veterinary medical science2017

Effect of burdock extract on physical performance and physiological fatigue in mice.

Wen-Chyuan Chen, Yi-Ju Hsu, Mon-Chien Lee, Hua Shuai Li, Chun-Sheng Ho, Chi-Chang Huang, Fu-An Chen

Abstract read
In one paragraph

Article in The Journal of veterinary medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen-Chyuan ChenCenter for General Education, Chang Gung University of Science and Technology, Taoyuan 33301, Taiwan.
Yi-Ju HsuGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan.
Mon-Chien LeeGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan.
Hua Shuai LiGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan.
Chun-Sheng HoDivision of Physical Medicine and Rehabilitation, Lo-Hsu Foundation, Inc., Lotung Poh-Ai Hospital, Yilan 26546, Taiwan.
Chi-Chang HuangGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan.
Fu-An ChenDepartment of Pharmacy & Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 90741, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burdock (BD) is a common vegetable with many pharmacological properties. However, few studies have examined the effect of BD on exercise performance and physical fatigue. We aimed to evaluate the potential beneficial effects of BD on fatigue and ergogenic functions following physical challenge in mice.

methodsMale ICR mice were divided into four groups to receive either vehicle, or BD at 348.5, 697 or 1,742.5 mg/kg/day, by daily oral gavage for 4 weeks. Exercise performance and fatigue were evaluated from forelimb grip strength, exhaustive swimming time, and post-exercise levels of physical fatigue-related biomarkers serum lactate, ammonia, glucose, and creatine kinase (CK).

resultsBD supplementation elevated endurance and grip strength in a dose-dependent manner. It also significantly decreased lactate, ammonia, and CK levels after physical challenge. In addition, BD supplementation had few subchronic toxic effects.

conclusionsSupplementation with BD has a wide spectrum of bioactive effects, including health promotion, performance improvement, and fatigue reduction.

Indexed as

ArctiumAmmoniaAnimalsBlood GlucoseCreatine KinaseDose-Response Relationship, DrugFatigueLactic AcidMaleMiceMice, Inbred ICRPhysical Conditioning, AnimalPhysical EndurancePlant ExtractsAmmoniaBlood GlucoseCreatine KinaseLactic AcidPlant Extractsanti-fatigueburdockendurancegrip strengthtoxicity

Identifiers

PMID28890521
PMCPMC5658563

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.