Evidence map›Paper›PMID 28890385›Full record

ArticleProstaglandins & other lipid mediators2017

Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A

Ahmad Hanif, Matthew L Edin, Darryl C Zeldin, Christophe Morisseau, John R Falck, Catherine Ledent, Stephen L Tilley, Mohammed A Nayeem

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Prostaglandins & other lipid mediators, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Adenosine AMolecular and cellular biochemistry · 2021
    Article
  3. Article
  4. Frontiers in pharmacology · 2020
    Article
  5. Role of oxylipins in cardiovascular diseases.Acta pharmacologica Sinica · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Ahmad HanifBasic Pharmaceutical Sciences, School of Pharmacy, Center for Basic and Translational Stroke Research, West Virginia University, Morgantown, WV, United States.
Matthew L EdinDivision of Intramural Research, NIEHS/NIH, Research Triangle Park, NC, United States.
Darryl C ZeldinDivision of Intramural Research, NIEHS/NIH, Research Triangle Park, NC, United States.
Christophe MorisseauUniversity of California at Davis, One Shields Avenue, Davis, CA, United States.
John R FalckBiochemistry, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Catherine LedentIRIBHN, Universite Libre de Bruxelles, Belgium.
Stephen L TilleyDivision of Pulmonary and Critical Care Medicine, UNC at Chapel Hill, Chapel Hill, NC, United States.
Mohammed A NayeemBasic Pharmaceutical Sciences, School of Pharmacy, Center for Basic and Translational Stroke Research, West Virginia University, Morgantown, WV, United States. Electronic address: mnayeem@hsc.wvu.edu.
Triangle · USWest Virginia University · USThe University of Texas Southwestern Medical Center · USUniversité Libre de Bruxelles · BEUniversity of California, Davis · USUniversity of North Carolina Health Care · US

Funding

Characterization And Functional Significance Of P450 Arachidonate EpoxygenasesZIAES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$18.6M
P450 Arachidonate EpoxygenasesZ01ES025034 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1995 to 2008
$2.2M
Role of Cyp2j-epoxygenases, sEH and PPARs in adenosine-induced vascular responseR01HL114559 · NHLBI · WEST VIRGINIA UNIVERSITY · PI NAYEEM, MOHAMMED A · 2013 to 2017
$1.5M
Intramural NIH HHS Z01 ES025034NHLBI NIH HHS R01 HL114559
6 · The paper itself

Abstract

Coronary reactive hyperemia (CRH) protects the heart against ischemia. Adenosine A

Indexed as

Adenosine A2 Receptor AntagonistsAnimalsBenzoatesCoronary VesselsEnzyme InhibitorsEpoxide HydrolasesHyperemiaMiceMice, Inbred C57BLOxylipinsReceptor, Adenosine A2ASolubilityUrea4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acidAdenosine A2 Receptor AntagonistsBenzoatesEnzyme InhibitorsEpoxide HydrolasesOxylipinsReceptor, Adenosine A2AUreaAdenosine A(2A) receptorCoronary reactive hyperemiaHeart perfusate oxylipinsPlasma oxylipinsSoluble epoxide hydrolaseω-hydroxylases

Identifiers

PMID28890385
PMCPMC5635996
OpenAlexW2751640232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.