ArticleCell chemical biology2017
MitoNeoD: A Mitochondria-Targeted Superoxide Probe.
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In one paragraph
Article in Cell chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 97 citations in OpenAlex.
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- Dual-action mitochondria-targeted prodrugs that both deplete mitochondrial glutathione and deliver a toxic payload to the matrix.European journal of medicinal chemistry · 2026Article
- Increased mROS Generation Associates With Cardiovascular Risk in BioHEART-CT PBMCs.Clinical and translational science · 2026Article
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- Triphenylphosphonium is an effective targeting moiety for plant mitochondria.The New phytologist · 2025Article
- Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis.Science advances · 2025Article
- Mitochondria reactive oxygen species signaling-dependent immune responses in macrophages and T cells.Immunity · 2025Review
- Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis.Journal of lipid research · 2025Article
- Mitochondrial Dysfunction and Atherosclerosis: The Problem and the Search for Its Solution.Biomedicines · 2025Review
- Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation.Nature metabolism · 2025Article
- Modular Design and Scaffold-Synthesis of Multi-Functional Fluorophores for Targeted Cellular Imaging and Pyroptosis.Angewandte Chemie (International ed. in English) · 2025Article
- Redefining Molecular Probes for Monitoring Subcellular Environment: A Perspective.Analytical chemistry · 2024Review
- Promising tools into oxidative stress: A review of non-rodent model organisms.Redox biology · 2024Review
- Revisiting reactive oxygen species production in hypoxia.Pflugers Archiv : European journal of physiology · 2024Review
- Ten "Cheat Codes" for Measuring Oxidative Stress in Humans.Antioxidants (Basel, Switzerland) · 2024Review
- Role of Na/K-ATPase α1 caveolin-binding motif in adipogenesis.American journal of physiology. Cell physiology · 2024Article
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 6 institutions in 2 countries.
Maria M ShchepinovaWestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Andrew G CairnsWestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Tracy A PrimeMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Angela LoganMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Andrew M JamesMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Andrew R HallMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Sara VidoniMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Sabine ArndtMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Stuart T CaldwellWestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Hiran A PragMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Victoria R PellDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Thomas KriegDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
John F MulveyDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Pooja YadavSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
James N CobleyDivision of Sport and Exercise Sciences, Abertay University, Dundee DD1 1HG, UK.
Thomas P BrightMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK.
Hans M SennWestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK.
Robert F AndersonSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Michael P MurphyMRC Mitochondrial Biology Unit, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK. Electronic address: mpm@mrc-mbu.cam.ac.uk.
Richard C HartleyWestCHEM School of Chemistry, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address: richard.hartley@glasgow.ac.uk.
University of Cambridge · GBUniversity of Glasgow · GBMRC Mitochondrial Biology Unit · GBAddenbrooke's Hospital · GBUniversity of Auckland · NZAbertay University · GB
Funding
Medical Research Council MC_U105663142Wellcome Trust 110158/Z/15/Z
Abstract
Mitochondrial superoxide (O
Indexed as
AnimalsBiological TransportCell LineDNAMaleMass SpectrometryMiceMitochondriaModels, MolecularMolecular ProbesNucleic Acid ConformationOxidation-ReductionSuperoxidesDNAMolecular ProbesSuperoxidesexomarkerhydroethidinemitochondriamitochondria-targetingMitoSOXROS measurementsuperoxidetriphenylphosphonium
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What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.