Evidence map›Paper›PMID 28890234›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2017

Calibration of a lactic-acid model for simulating biofilm-induced degradation of the dentin-composite interface.

Laikuan Zhu, Yuping Li, Carola A Carrera, Yung-Chung Chen, Mingyu Li, Alex Fok

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Article in Dental materials : official publication of the Academy of Dental Materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laikuan ZhuDepartment of Endodontics and Operative Dentistry, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai, China. Electronic address: zhulk1997@163.com.
Yuping LiMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Carola A CarreraMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Yung-Chung ChenInstitute of Oral Medicine, College of Medicine National Cheng Kung University Taiwan, Taiwan.
Mingyu LiShanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology, Shanghai, China.
Alex FokMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA. Electronic address: alexfok@umn.edu.

Funding

Interactions Between Oral Biofilms and Dental Resin CompositesR01DE021366 · NIDCR · UNIVERSITY OF MINNESOTA · PI FOK, ALEX SIU-LUN, JONES, ROBERT SIMON · 2010 to 2013
$1.5M
NIDCR NIH HHS R01 DE021366
6 · The paper itself

Abstract

objectiveTo verify and calibrate a chemical model for simulating the degradation of the dentin-composite interface induced by multi-species oral biofilms in vitro.

methodsDentin-composite disks (5-mm dia.×2-mm thick) were made from bovine incisor roots and filled with either Z100™ (Z100) or Filtek™ LS (LS) composite. The disks, which were covered with nail varnish, but with one of the dentin-composite margins exposed, were immersed in lactic acid solution at pH 4.5 for up to 48h. Diametral compression was performed to measure the reduction in bond strength of the dentin-composite disks following acid challenge. Scanning electron microscopy (SEM) was used to examine decalcification of dentin and fracture modes of the disks. To better understand the degradation process, micro-computed tomography, in combination with a radiopaque dye (AgNO

resultsAfter 48h of acid challenge, the debonding load of both the LS- and Z100-filled disks reduced significantly (p<0.05). In the Z100-filled disks, debonding mostly occurred at the adhesive-dentin interface, while in the LS-filled disks, this happened at the adhesive-composite interface, instead. The degree of dentin demineralization, the reduction in debonding load and the modes of failure observed were very similar to those induced by multi-species oral biofilms found in the previous work. Leakage of AgNO SIGNIFICANCE: The chemical model with lactic acid used in this study can induce degradation to the dentin-composite interface similar to those produced by multi-species biofilms. With appropriate calibration, this could provide an effective in vitro method for ageing composite restorations in assessing their potential clinical performance.

Indexed as

BiofilmsDental Restoration FailureAnimalsCalibrationCattleComposite ResinsDental LeakageDental Restoration, PermanentDentinHydrogen-Ion ConcentrationIn Vitro TechniquesLactic AcidMaterials TestingMicroscopy, Electron, ScanningSilicon DioxideSurface PropertiesComposite ResinsFiltek LS Low Shrink resinLactic AcidSilicon DioxideZ100 composite resinZirconiumBond strengthComposite resinsInterfacial degradationMicroleakageSecondary caries

Identifiers

PMID28890234
PMCPMC5679312

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