ArticlePsychological medicine2018
Leukocyte telomere length and personality: associations with the Big Five and Type D personality traits.
Article in Psychological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Infant buccal telomere length: associations with maternal distress in pregnancy and offspring temperament.Frontiers in public health · 2025Article
- Associations among temperament characteristics and telomere length and attrition rate in early childhood.Developmental psychology · 2024Article
- A pilot study examining the relationship between chronic heroin use and telomere length among individuals of African ancestry.Pharmacology, biochemistry, and behavior · 2023Article
- Evaluation of Coping Strategies among Students with Type D Personality.International journal of environmental research and public health · 2022Article
- Stress reactivity elicits a tissue-specific reduction in telomere length in aging zebrafish (Danio rerio).Scientific reports · 2021Article
- The associations of hostility and defensiveness with telomere length are influenced by sex and health status.Biology of sex differences · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Backgrounds Accelerated cellular ageing, which can be examined by telomere length (TL), may be an overarching mechanism underlying the association between personality and adverse health outcomes. This 6-year longitudinal study examined the relation between personality and leukocyte telomere length (LTL) across time among adults with a wide age-range.
methodsData from the Netherlands Study of Depression and Anxiety were used and included patients with a depression and/or anxiety disorder and healthy controls. Overall, 2936 persons (18-65 years, 66% female) had data on LTL at baseline and 1883 persons had LTL at 6-year follow-up. The Big Five personality traits (neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness) and Type D personality were assessed.
resultsNeuroticism was negatively (B = -2.11, p = 0.03) and agreeableness was positively (B = 3.84, p = 0.03) related to LTL measured across two time points, which became just non-significant after adjusting for somatic health, lifestyle factors, and recent life stress (B = -1.99, p = 0.06; and B = 3.01, p = 0.10). Type D personality was negatively (B = -50.16, p < 0.01) related to LTL across two time points, which still remained statistically significant after full adjustment (B = -47.37, p = 0.01). Associations did not differ by age, gender, and current psychiatric status.
conclusionsThe Big Five traits high neuroticism and low agreeableness, and Type D personality were associated with shorter LTL measured across a 6-year period. Associations with the Big Five traits became non-significant after controlling for somatic health, lifestyle factors, and recent life stress, yet similar trends were observed. Type D personality remained independently associated with shorter LTL after full adjustment.
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