Evidence map›Paper›PMID 28889802›Full record

ArticlePsychological medicine2018

Prevalence and clinical relevance of interview-assessed psychosis-risk symptoms in the young adult community.

Frauke Schultze-Lutter, Chantal Michel, Stephan Ruhrmann, Benno G Schimmelmann

Abstract read
In one paragraph

Article in Psychological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

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34citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  3. Pathways to professional mental care in the Swiss young adult community: a case-control study.European archives of psychiatry and clinical neuroscience · 2025
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Frauke Schultze-LutterUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern,Bern,Switzerland.
Chantal MichelUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern,Bern,Switzerland.
Stephan RuhrmannDepartment of Psychiatry and Psychotherapy,University of Cologne,Cologne,Germany.
Benno G SchimmelmannUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern,Bern,Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn efficient indicated prevention of psychotic disorders requires valid risk criteria that work in both clinical and community samples. Yet, ultra-high risk and basic symptom criteria were recently recommended for use in clinical samples only. Their use in the community was discouraged for lack of knowledge about their prevalence, clinical relevance and risk factors in non-clinical, community settings when validly assessed with the same instruments used in the clinic.

methodsUsing semi-structured telephone interviews with established psychosis-risk instruments, we studied the prevalence of psychosis-risk symptoms and criteria, their clinical relevance (using presence of a non-psychotic mental disorder or of functional deficits as proxy measures) and their risk factors in a random, representative young adult community sample (N=2683; age 16-40 years; response rate: 63.4%).

resultsThe point-prevalence of psychosis-risk symptoms was 13.8%. As these mostly occurred too infrequent to meet frequency requirements of psychosis-risk criteria, only 2.4% of participants met psychosis-risk criteria. A stepwise relationship underlay the association of ultra-high risk and basic symptoms with proxy measures of clinical relevance, this being most significant when both occurred together. In line with models of their formation, basic symptoms were selectively associated with age, ultra-high risk symptoms with traumatic events and lifetime substance misuse.

conclusionsPsychosis-risk criteria were uncommon, indicating little risk of falsely labelling individuals from the community at-risk for psychosis. Besides, both psychosis-risk symptoms and criteria seem to possess sufficient clinical relevance to warrant their broader attention in clinical practice, especially if ultra-high risk and basic symptoms occur together.

Indexed as

AdolescentAdultFemaleHumansMalePrevalencePsychiatric Status Rating ScalesPsychotic DisordersRegression AnalysisRisk AssessmentRisk FactorsSwitzerlandYoung AdultBasic symptomsclinical relevancegeneral populationprevalencepsychosesultra-high risk

Identifiers

PMID28889802
PMCPMC6088777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.