ArticleLasers in medical science2018
Efficiency of soft tissue incision with a novel 445-nm semiconductor laser.
Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 57 citations in OpenAlex.
- Wound healing after therapy of oral potentially malignant disorders with a 445-nm semiconductor laser: a randomized clinical trial.Clinical oral investigations · 2023Trial
- Efficacy of a 445 nm wavelength laser in the surgical treatment of chronic otitis media.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Enhancing the Efficacy of Noncontact Laser Ablation of Weakly Absorbing Cholesteatoma Tissue Using a Blood Layer.Lasers in surgery and medicine · 2026Article
- Precise ablation of cholesteatoma using a 445-nm diode laser.Scientific reports · 2026Article
- Management of Gingival Overgrowth During Orthodontic Treatment Using a Blue Laser: A Case Report.Clinical case reports · 2026Article
- In silico design of blue laser soft tissue vaporization with optimized optical power efficiency and mitigated thermal side effects.Lasers in medical science · 2025Article
- Periradicular Temperature Changes and Risk Management During Heat-Inducing Endodontic Disinfection Procedures In Vitro.Journal of clinical medicine · 2025Article
- Antimicrobial effect of 2.5% sodium hypochlorite irradiated with the 445 Nm diode laser against bacterial biofilms in root canal - in vitro pilot study.Lasers in medical science · 2025Article
- Article
- Conventional vs. diode laser stapedotomy: audiological outcomes and clinical safety.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Observational
- The Effect of Two Different Wavelengths of Diode Laser on the Shear Bond Strength of Composite to Dental Enamel after Bleaching Process: An In Vitro Study.Bioengineering (Basel, Switzerland) · 2024Article
- In Vitro Assessment of SWEEPS and Antimicrobial Photodynamic Therapy Alone or in Combination for EradicatingPharmaceutics · 2023Article
- Comparative study of soft tissue surgery by visible and infrared laser radiation.Lasers in medical science · 2023Article
- Use of lasers in gastrointestinal endoscopy: a review of the literature.Lasers in medical science · 2023Review
- The Impact of Laser Thermal Effect on Histological Evaluation of Oral Soft Tissue Biopsy: Systematic Review.Dentistry journal · 2023Review
- Treatment of Gingival Growth Due to Amlodipine Use With a 445-nm Diode Laser: A Case Report.Cureus · 2022Article
- In vitro evaluation of the safety and efficacy of a high-power 450-nm semiconductor blue laser in the treatment of benign prostate hyperplasia.Lasers in medical science · 2022Article
- Thermal effect of a 445 nm diode laser on five dental implant systems: an in vitro study.Scientific reports · 2021Article
- Quantitative determination of cut efficiency during soft tissue surgery using diode lasers in the wavelength range between 400 and 1500 nm.Lasers in medical science · 2021Article
- The impact of the laser fiber-tissue distance on histological parameters in a porcine kidney model.World journal of urology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using a 445-nm semiconductor laser for tissue incision, an effective cut is expected due to the special absorption properties of blue laser light in soft tissues. The aim of the present study was the histological evaluation of tissue samples after incision with a 445-nm diode laser. Forty soft tissue specimens were obtained from pork oral mucosa and mounted on a motorized linear translation stage. The handpiece of a high-frequency surgery device, a 970-nm semiconductor laser, and a 445-nm semiconductor laser were connected to the slide, allowing a constant linear movement (2 mm/s) and the same distance of the working tip to the soft tissue's surface. Four incisions were made each: (I) 970-nm laser with conditioned fiber tip, contact mode at 3-W cw; (II-III): 445-nm laser with non-conditioned fiber tip, contact mode at 2-W cw, and non-contact mode (1 mm) at 2 W; and (IV): high-frequency surgery device with straight working tip, 90° angulation, contact mode at 50 W. Histological analysis was performed after H&E staining of the embedded specimens at 35-fold magnification. The comparison of the incision depths showed a significant difference depending on the laser wavelength and the selected laser parameters. The highest incision depth was achieved with the 445-nm laser contact mode (median depth 0.61 mm, min 0.26, max 1.17, interquartile range 0.58) (p < 0.05) with the lowest amount of soft tissue denaturation (p < 0.05). The lowest incision depth was measured for the high-frequency surgical device (median depth 0.36 mm, min 0.12, max 1.12, interquartile range 0.23) (p < 0.05). Using a 445-nm semiconductor laser, a higher cutting efficiency can be expected when compared with a 970-nm diode laser and high-frequency surgery. Even the 445-nm laser application in non-contact mode shows clinically acceptable incision depths without signs of extensive soft tissue denaturation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.