Evidence map›Paper›PMID 28889240›Full record

SynthesisObesity surgery2017

Ursodeoxycholic Acid in the Prevention of Gallstone Formation After Bariatric Surgery: an Updated Systematic Review and Meta-analysis.

Dimitrios E Magouliotis, Vasiliki S Tasiopoulou, Alexis A Svokos, Konstantina A Svokos, Christina Chatedaki, Eleni Sioka, Dimitris Zacharoulis

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  18. [Cholecystolithiasis and intestinal bypass procedures].Chirurgie (Heidelberg, Germany) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dimitrios E MagouliotisDepartment of Surgery, University Hospital of Larissa, Viopolis, 411 10, Larissa, Greece. dmagouliotis@gmail.com.
Vasiliki S TasiopoulouFaculty of Medicine, School of Health Sciences, University of Thessaly Viopolis Larissa Greece, Viopolis, Larissa, Greece.
Alexis A SvokosRiverside Regional Medical Center, Newport News, VA, USA.
Konstantina A SvokosThe Warren Alpert Medical School of Brown University, Providence, RI, USA.
Christina ChatedakiDepartment of Microbiology, University Hospital of Larissa, Larissa, Greece.
Eleni SiokaDepartment of Surgery, University Hospital of Larissa, Viopolis, 411 10, Larissa, Greece.
Dimitris ZacharoulisDepartment of Surgery, University Hospital of Larissa, Viopolis, 411 10, Larissa, Greece.
University Hospital of Larissa · GRBrown University · USRiverside Regional Medical Center · USUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to review the available literature on obese patients treated with ursodeoxycholic acid (UDCA) in order to prevent gallstone formation after bariatric surgery. A systematic literature search was performed in PubMed, Cochrane library, and Scopus databases, in accordance with the PRISMA guidelines. Eight studies met the inclusion criteria incorporating 1355 patients. Random-effects meta-analysis showed a lower incidence of gallstone formation in patients taking UDCA. Subgroup analysis reported fewer cases of gallstone disease in the UDCA group in relation to different bariatric procedures, doses of administered UDCA, and time from bariatric surgery. Adverse events were similar in both groups. Fewer patients required cholecystectomy in UDCA group. No deaths were reported. The administration of UDCA after bariatric surgery seems to prevent gallstone formation.

Indexed as

AdultBariatric SurgeryChemopreventionCholecystectomyGallstonesHumansObesity, MorbidUrsodeoxycholic AcidUrsodeoxycholic AcidBariatric surgeryGallstoneGallstone preventionMeta-analysisUrsodeoxycholic acid

Identifiers

PMID28889240
OpenAlexW2755711258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.