ArticleMagnetic resonance imaging2018
Test-retest reliability of cerebral blood flow in healthy individuals using arterial spin labeling: Findings from the EMBARC study.
Article in Magnetic resonance imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Nitric oxide synthase inhibition in healthy adults reduces regional and total cerebral macrovascular blood flow and microvascular perfusion.The Journal of physiology · 2021Trial
- Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness.Communications biology · 2025Article
- Cerebral blood flow is associated with plasma and PET biomarkers of tau pathology in middle age.Brain communications · 2025Article
- Multi-cohort, multi-sequence harmonisation for cerebrovascular brain age.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Reproducibility of arterial spin labeling cerebral blood flow image processing: A report of the ISMRM open science initiative for perfusion imaging (OSIPI) and the ASL MRI challenge.Magnetic resonance in medicine · 2024Article
- Psilocybin-induced changes in cerebral blood flow are associated with acute and baseline inter-individual differences.Scientific reports · 2023Article
- Whole-Cerebrum distortion-free three-dimensional pseudo-continuous arterial spin labeling at 7T.NeuroImage · 2023Article
- Depression, stress and regional cerebral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Test-retest reliability of 3D velocity-selective arterial spin labeling for detecting normal variations of cerebral blood flow.NeuroImage · 2023Article
- ASL-BIDS, the brain imaging data structure extension for arterial spin labeling.Scientific data · 2022Article
- Test-retest reliability of arterial spin labelling for cerebral blood flow in older adults with small vessel disease.Translational stroke research · 2022Article
- Perilesional Perfusion in Chronic Stroke-Induced Aphasia and Its Response to Behavioral Treatment Interventions.Neurobiology of language (Cambridge, Mass.) · 2022Article
- Comparison of test-retest reliability of BOLD and pCASL fMRI in a two-center study.BMC medical imaging · 2022Article
- High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 1: Perfusion and Diffusion Techniques.Frontiers in oncology · 2022Review
- Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis.Brain : a journal of neurology · 2021Review
- Structural and Functional Brain Parameters Related to Cognitive Performance Across Development: Replication and Extension of the Parieto-Frontal Integration Theory in a Single Sample.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Review
- Discovery and replication of cerebral blood flow differences in major depressive disorder.Molecular psychiatry · 2020Article
- Cerebral Perfusion Effects of Cognitive Training and Transcranial Direct Current Stimulation in Mild-Moderate TBI.Frontiers in neurology · 2020Article
- Psychiatric neuroimaging research in Brazil: historical overview, current challenges, and future opportunities.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2020Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
introductionPrevious investigations of test-retest reliability of cerebral blood flow (CBF) at rest measured with pseudo-continuous Arterial Spin Labeling (pCASL) demonstrated good reliability, but are limited by the use of similar scanner platforms. In the present study we examined test-retest reliability of CBF in regions implicated in emotion and the default mode network. MATERIAL AND
methodsWe measured absolute and relative CBF at rest in thirty-one healthy subjects in two scan sessions, one week apart, at four different sites and three different scan platforms. We derived CBF from pCASL images with an automated algorithm and calculated intra-class correlation coefficients (ICCs) across sessions for regions of interest. In addition, we investigated site effects.
resultsFor both absolute and relative CBF measures, ICCs were good to excellent (i.e. >0.6) in most brain regions, with highest values observed for the subgenual anterior cingulate cortex and ventral striatum. A leave-one-site-out cross validation analysis did not show a significant effect for site on whole brain CBF and there was no proportional bias across sites. However, a significant site effect was present in the repeated measures ANOVA.
conclusionsThe high test-retest reliability of CBF measured with pCASL in a range of brain regions implicated in emotion and salience processing, emotion regulation, and the default mode network, which have been previously linked to depression symptomatology supports its use in studies that aim to identify neuroimaging biomarkers of treatment response.
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