ArticleAmerican heart journal2017
Sex-based differences in quality of care and outcomes in a health system using a standardized STEMI protocol.
Article in American heart journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Interaction of Operator-Patient Sex on Peri-Procedural Treatments and Major Coronary Outcomes After Percutaneous Coronary Intervention.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
- Narrowing sex differences in pharmacotherapy following invasive angiography for coronary artery disease between 2017 and 2024.European heart journal open · 2026Article
- Sex disparities in STEMI pathophysiology: Presentation, treatments, and outcomes.Global cardiology science & practice · 2026Review
- Clinical outcomes and discharge disposition in nonagenarians with ST-elevation myocardial infarction.American heart journal · 2025Article
- Sex differences in ST-segment elevation myocardial infarction patients treated by primary percutaneous intervention.Open heart · 2025Article
- Demographics and regional trends of ischemic heart disease-related mortality in older adults in the United States, 1999-2020.PloS one · 2025Article
- Gender inequalities in secondary prevention of cardiovascular disease: a scoping review.International journal for equity in health · 2024Article
- Ensemble machine learning for predicting in-hospital mortality in Asian women with ST-elevation myocardial infarction (STEMI).Scientific reports · 2024Article
- Review
- Review
- Mortality of patients with ST-segment-elevation myocardial infarction without standard modifiable risk factors among patients without known coronary artery disease: Age-stratified and sex-related analysis from nationwide readmissions database 2010-2014.American journal of preventive cardiology · 2023Article
- Trends and Outcomes of ST-Segment-Elevation Myocardial Infarction Among Young Women in the United States.Journal of the American Heart Association · 2023Article
- What underlies sex differences in heart failure onset within the first year after a first myocardial infarction?Frontiers in cardiovascular medicine · 2023Article
- In-hospital risk stratification algorithm of Asian elderly patients.Scientific reports · 2022Article
- Article
- Are we any WISER yet? Progress and contemporary need for smart trials to include women in coronary artery disease trials.Contemporary clinical trials · 2022Review
- Association between race/ethnicity and income on the likelihood of coronary revascularization among postmenopausal women with acute myocardial infarction: Women's health initiative study.American heart journal · 2022Article
- Coronary Arterial Function and Disease in Women With No Obstructive Coronary Arteries.Circulation research · 2022Review
- The Diabetes-Cardiovascular Connection in Women: Understanding the Known Risks, Outcomes, and Implications for Care.Current diabetes reports · 2022Review
- Sex Differences in Characteristics, Treatments, and In-hospital Outcomes of Patients Undergoing Coronary Angiography or Intervention.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundRecent data from the National Cardiovascular Data Registry indicate that women with ST-segment-elevation myocardial infarction (STEMI) continue to have higher mortality and reported delays in treatment compared with men. We aimed to determine whether the sex difference in mortality exists when treatment disparities are reduced.
methodsUsing a prospective regional percutaneous coronary intervention (PCI)-based STEMI system database with a standardized STEMI protocol, we evaluated baseline characteristics, treatment, and clinical outcomes of STEMI patients stratified by sex.
resultsFrom March 2003 to January 2016, 4,918 consecutive STEMI patients presented to the Minneapolis Heart Institute at Abbott Northwestern Hospital regional STEMI system including 1,416 (28.8%) women. Compared with men, women were older (68.4 vs 60.9 years) with higher rates of hypertension (66.7% vs 55.7%), diabetes (21.7% vs 17.4%), and cardiogenic shock (11.5% vs 8.0%) (all P < .001). Pre-revascularization medications and PCI were performed with same frequencies, but women were less likely to receive statin or antiplatelet therapy at discharge. After age adjustment, women had similar in-hospital mortality to men (5.1% vs 4.8%, P = .60) despite slightly longer door-to-balloon time (95 vs 92 minutes, P = .004). Five-year follow-up confirmed absence of a sex disparity in age-adjusted survival post-STEMI.
conclusionsPreviously reported treatment disparities between men and women are diminished in a regional PCI-based STEMI system using a standardized STEMI protocol. No sex differences in short-term or long-term age-adjusted mortality are present in this registry despite some treatment disparities. These results suggest that STEMI health care disparities and mortality in women can be improved using STEMI protocols and systems.
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