Evidence map›Paper›PMID 28887784›Full record

ReviewFamilial cancer2018

Pancreatic neuroendocrine tumor in a patient with a TSC1 variant: case report and review of the literature.

Parisa Mortaji, Katherine T Morris, Von Samedi, Steven Eberhardt, Shawnia Ryan

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Familial cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Parisa MortajiUniversity of New Mexico School of Medicine, Albuquerque, NM, USA.
Katherine T MorrisDepartment of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Von SamediDepartment of Pathology, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Steven EberhardtDepartment of Radiology, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Shawnia RyanThe University of New Mexico Comprehensive Cancer Center, 1201 Camino de Salud, MSC07 4025, Albuquerque, NM, 87131, USA. shawniaryan@unm.edu.ORCID 0000-0002-4283-4850
University of New Mexico · USUniversity of Oklahoma Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of pancreatic neuroendocrine tumors (PNETs) are sporadic while 10-15% are attributable to one of several familial cancer syndromes. Hereditary forms are more commonly associated with Multiple Endocrine Neoplasia Type I and von Hippel Lindau Syndrome. However, patients with Tuberous sclerosis complex also have an increased incidence of PNETs. More often this has been reported in patients with TSC2 variants. In this case report, we summarize the literature regarding PNETs associated with Tuberous sclerosis complex, as well as present a case of a patient with a TSC1 variant and a PNET. This case highlights the association of TSC1 gene variants with these tumors and emphasizes the importance of considering such diagnoses in this patient population.

Indexed as

AdultAngiomyolipomaFemaleGerm-Line MutationHumansIntestinal NeoplasmsKidneyKidney NeoplasmsNeuroendocrine TumorsPancreasPancreatic NeoplasmsStomach NeoplasmsTomography, X-Ray ComputedTuberous SclerosisTuberous Sclerosis Complex 1 ProteinTSC1 protein, humanTuberous Sclerosis Complex 1 ProteinHereditary cancer syndromesPancreatic neuroendocrine tumorsTSC1Tuberous sclerosis complex

Identifiers

PMID28887784
OpenAlexW2756309942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.