Evidence map›Paper›PMID 28887761›Full record

ArticleAnnals of nuclear medicine2017

Textural features and SUV-based variables assessed by dual time point 18F-FDG PET/CT in locally advanced breast cancer.

Ana María Garcia-Vicente, David Molina, Julián Pérez-Beteta, Mariano Amo-Salas, Alicia Martínez-González, Gloria Bueno, María Jesús Tello-Galán, Ángel Soriano-Castrejón

Abstract read
In one paragraph

Article in Annals of nuclear medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Clinicopathologic and metabolic variables fromAnnals of nuclear medicine · 2025
    Article
  2. Effects of Tracer Uptake Time in Non-Small Cell Lung CancerJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  3. Application progress of multiple imaging modalities in Takayasu arteritis.The international journal of cardiovascular imaging · 2021
    Review
  4. Review
  5. Article
  6. BaselineEuropean radiology · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana María Garcia-VicenteNuclear Medicine Department, University General Hospital, C/Obispo Rafael Torija s/n. 13005, Ciudad Real, Spain. angarvice@yahoo.es.
David MolinaMathematical Oncology Laboratory (MôLAB), Universidad de Castilla-La Mancha, Ciudad Real, Spain.
Julián Pérez-BetetaMathematical Oncology Laboratory (MôLAB), Universidad de Castilla-La Mancha, Ciudad Real, Spain.
Mariano Amo-SalasDepartment of Mathematics, University of Castilla-La Mancha, Ciudad Real, Spain.
Alicia Martínez-GonzálezMathematical Oncology Laboratory (MôLAB), Universidad de Castilla-La Mancha, Ciudad Real, Spain.
Gloria BuenoVISILAB Group, School of Industrial Engineering, Universidad de Castilla-La Mancha, Ciudad Real, Spain.
María Jesús Tello-GalánNuclear Medicine Department, University General Hospital, C/Obispo Rafael Torija s/n. 13005, Ciudad Real, Spain.
Ángel Soriano-CastrejónNuclear Medicine Department, University General Hospital, C/Obispo Rafael Torija s/n. 13005, Ciudad Real, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the influence of dual time point 18F-FDG PET/CT in textural features and SUV-based variables and their relation among them.

methodsFifty-six patients with locally advanced breast cancer (LABC) were prospectively included. All of them underwent a standard 18F-FDG PET/CT (PET-1) and a delayed acquisition (PET-2). After segmentation, SUV variables (SUVmax, SUVmean, and SUVpeak), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were obtained. Eighteen three-dimensional (3D) textural measures were computed including: run-length matrices (RLM) features, co-occurrence matrices (CM) features, and energies. Differences between all PET-derived variables obtained in PET-1 and PET-2 were studied.

resultsSignificant differences were found between the SUV-based parameters and MTV obtained in the dual time point PET/CT, with higher values of SUV-based variables and lower MTV in the PET-2 with respect to the PET-1. In relation with the textural parameters obtained in dual time point acquisition, significant differences were found for the short run emphasis, low gray-level run emphasis, short run high gray-level emphasis, run percentage, long run emphasis, gray-level non-uniformity, homogeneity, and dissimilarity. Textural variables showed relations with MTV and TLG.

conclusionSignificant differences of textural features were found in dual time point 18F-FDG PET/CT. Thus, a dynamic behavior of metabolic characteristics should be expected, with higher heterogeneity in delayed PET acquisition compared with the standard PET. A greater heterogeneity was found in bigger tumors.

Indexed as

Positron Emission Tomography Computed TomographyBiological TransportBreast NeoplasmsFluorodeoxyglucose F18GlycolysisHumansImage Processing, Computer-AssistedRetrospective StudiesTime FactorsTumor BurdenFluorodeoxyglucose F18Breast cancerDual time point 18F-FDG PET/CTTextural featuresTumor heterogeneity

Identifiers

PMID28887761
PMCPMC5691106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.