Evidence map›Paper›PMID 28887725›Full record

ArticleWorld journal of microbiology & biotechnology2017

Recombinant flagellin-PAL fusion protein of Legionella pneumophila induced cell-mediated and protective immunity against bacteremia in BALB/c mice.

Ashraf Mohabati Mobarez, Roya Ahmadrajabi, Nima Khoramabadi, Ali Hatef Salmanian

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ashraf Mohabati MobarezDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. mmmobarez@modares.ac.ir.
Roya AhmadrajabiBam University of Medical Sciences, Bam, Iran.
Nima KhoramabadiDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Ali Hatef SalmanianNational Institutes for Genetic Engineering and Biotechnology, Tehran, Iran.
Tarbiat Modares University · IRBam University of Medical Sciences · IRNational Institute of Genetic Engineering and Biotechnology · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a new recombinant fusion protein composed of full-length Legionella pneumophila flagellin A and peptidoglycan-associated lipoprotein (PAL), rFLA-PAL, capable of inducing protective immunity against L. pneumophila. The recombinant protein was over expressed in Escherichia coli strain BL21 (DE3) using pET-28a (+) expression vector (pET28a-flaA-pal) and purified by Ni

Indexed as

Analysis of VarianceAnimalsAntibodies, BacterialAntigens, BacterialBacteremiaBacterial VaccinesCytokinesDisease Models, AnimalEscherichia coliFemaleFlagellinGene Expression Regulation, BacterialGenes, BacterialImmunity, CellularImmunizationInterferon-gammaAntibodies, BacterialAntigens, BacterialBacterial VaccinesCytokinesFlagellinIFNG protein, mouseInterferon-gammaInterleukin-12PeptidoglycanRecombinant Fusion ProteinsRecombinant ProteinsTumor Necrosis Factor-alphaFlagellin AFusion proteinLegionella pneumophilaPALVaccine

Identifiers

PMID28887725
OpenAlexW2756255988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.