Evidence map›Paper›PMID 28887669›Full record

ArticleAIDS and behavior2018

Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men.

Joëlla W Adams, Kendall J Bryant, E Jennifer Edelman, David A Fiellin, Julie R Gaither, Adam J Gordon, Kirsha S Gordon, Kevin L Kraemer, Matthew J Mimiaga, Don Operario and 4 more

Erratum issuedAbstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Joëlla W AdamsBrown University School of Public Health, Providence, RI, USA.
Kendall J BryantNational Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA.
E Jennifer EdelmanDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine, New Haven, CT, USA.
David A FiellinDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine, New Haven, CT, USA.
Julie R GaitherDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT, USA.
Adam J GordonCenter for Health Equity Research and Promotion, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA.
Kirsha S GordonVeterans Aging Cohort Study Coordinating Center, Veterans Administration Connecticut Healthcare System, West Haven, CT, USA.
Kevin L KraemerVA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Matthew J MimiagaBrown University School of Public Health, Providence, RI, USA.
Don OperarioBrown University School of Public Health, Providence, RI, USA.
Janet P TateDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine, New Haven, CT, USA.
Jacob J van den BergBrown University School of Public Health, Providence, RI, USA.
Amy C JusticeDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine, New Haven, CT, USA.
Brandon D L MarshallBrown University School of Public Health, Providence, RI, USA. brandon_marshall@brown.edu.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
Virology CoreP01AA019072 · NIAAA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2010 to 2024
$19.7M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Science/Technical CoreP2CHD041020 · NICHD · BROWN UNIVERSITY · PI ZHENCHAO QIAN · 2016 to 2026
$7.6M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Integrated Stepped Care for Unhealthy Alcohol Use in HIVU01AA020795 · NIAAA · YALE UNIVERSITY · PI FIELLIN, DAVID · 2011 to 2020
$5.2M
Minority Populations Resource CoreU24AA022000 · NIAAA · BROWN UNIVERSITY · PI OPERARIO, DON · 2012 to 2015
$1.9M
NIAAA NIH HHS P01 AA019072NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01 AA020795NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24 AA022000NIAID NIH HHS P30 AI042853NICHD NIH HHS P2C HD041020
6 · The paper itself

Abstract

Questionnaires over a 9-year study period (2002-2010) were used to characterize cannabis, stimulant, and alcohol use among 3099 HIV-infected men participating in the Veterans Aging Cohort Study (VACS) to determine whether use of these substances is associated with changes in the VACS Index, a validated prognostic indicator for all-cause mortality. At baseline, 18% of participants reported no substance use in the past year, 24% lower risk alcohol use only, 18% unhealthy alcohol use only, 15% cannabis use (with or without alcohol), and 24% stimulant use (with or without alcohol or cannabis). In adjusted longitudinal analyses, cannabis use [β = -0.97 (95% CI -1.93, 0.00), p = 0.048] was not associated with mortality risk, while stimulant use [1.08 (0.16, 2.00), p = 0.021] was associated with an increased mortality risk, compared to lower risk alcohol use. Our findings show no evidence of a negative effect of cannabis use on mortality risk, while stimulant use was associated with increased mortality risk among HIV-infected men. Interventions to reduce stimulant use in this patient population may reduce mortality.

Indexed as

AdultAlcohol DrinkingAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCannabisCentral Nervous System StimulantsCohort StudiesDrug UsersFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPrognosisProspective StudiesAnti-HIV AgentsCentral Nervous System StimulantsAlcoholCannabisDrug useHIV/AIDSMen who have sex with men

Identifiers

PMID28887669
PMCPMC5881942

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.