Evidence map›Paper›PMID 28887618›Full record

SynthesisNeuroradiology2017

Diagnostic value of 3D time-of-flight magnetic resonance angiography for detecting intracranial aneurysm: a meta-analysis.

Liu HaiFeng, Xu YongSheng, Xun YangQin, Dou Yu, Wang ShuaiWen, Lu XingRu, Lei JunQiang

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Short-TR Acquisition Time-of-flight MR Angiography with Deep Learning Reconstruction: Technical Feasibility and Initial Clinical Evaluation in Moyamoya Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. [Cardiovascular consequences of smoking : Imaging overview].Radiologie (Heidelberg, Germany) · 2022
    Review
  10. Article
  11. A comparison between the CS-TOF and the CTA/DSA for WEB device management.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  12. Article
  13. Thin Slice Unenhanced Brain CT Can Detect Aneurysms Larger than 7 mm.Journal of the Belgian Society of Radiology · 2022
    Article
  14. Article
  15. Techniques for Imaging Vascular Supply of Peripheral Nerves.Journal of brachial plexus and peripheral nerve injury · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Liu HaiFengDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China.
Xu YongShengDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China.
Xun YangQinEvidence-based Medicine Center, Lanzhou University, Lanzhou, China.
Dou YuDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China.
Wang ShuaiWenDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China.
Lu XingRuDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China.
Lei JunQiangDepartment of Radiology, First Hospital of LanZhou University, No. 1, Donggang West Road,Chengguan District, Lanzhou, Gansu, 730000, People's Republic of China. leijq2011@126.com.
Lanzhou University · CNFirst Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis meta-analysis is to comprehensively evaluate the diagnostic performance of three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) for detecting intracranial aneurysm (IA).

methodsPubMed, Embase, Web of Science, and the Cochrane library were systematically searched for retrieving eligible studies. Study inclusion, data extraction, and risk of bias assessment were performed by two researchers independently. Pooled sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the curve (AUC) were calculated to assess the diagnostic value. In addition, heterogeneity and subgroup analysis were carried out.

resultsIn total, 18 studies comprising 3463 patients were selected. The results of 3D-TOF-MRA for diagnosing IA were SEN 0.89 (95% CI 0.82-0.94), SPE 0.94 (0.86-0.97), PLR 13.79 (5.92-32.12), NLR 0.11 (0.07-0.19), DOR 121.90 (38.81-382.94), and AUC 0.96 (0.94-0.98), respectively. In the subgroup analysis, studies without subarachnoid hemorrhage (SAH) tend to perform statistical significantly better (P < 0.05) in detecting IAs than studies with SAH 0.99 (0.98-1.00) vs. 0.89 (0.86-0.91). The diagnostic value of studies with a two-image reconstruction method was higher than studies with only one image reconstruction method: 0.99 (0.98-1.00) vs. 0.91 (0.89-0.94) with P < 0.05. The 3D-TOF-MRA had better SEN in aneurysms > 3 mm than the aneurysms ≤ 3 mm in diameter: 0.89 (0.87-0.92) vs. 0.78 (0.71-0.84) with P < 0.05.

conclusionThis study demonstrated that 3D-TOF-MRA has an excellent diagnostic performance for the overall assessment of IA and may serve as an alternative for further patient management with IA.

Indexed as

Diagnosis, DifferentialHumansImaging, Three-DimensionalIntracranial AneurysmMagnetic Resonance Angiography3D-TOF-MRAIntracranial aneurysm (IA)Magnetic resonance angiography (MRA)Meta-analysisTime of flight (TOF)

Identifiers

PMID28887618
OpenAlexW2753941491

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.