ArticleScientific reports2017
The Arabidopsis MTP8 transporter determines the localization of manganese and iron in seeds.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 89 citations in OpenAlex.
- Functional characterization of transporter genes in rice node at single-cell resolution through multi-omics technologies.Genome biology · 2026Article
- Substrate and standard evaluation for correlative elemental mapping of biological samples by X-ray fluorescence microscopy and laser ablation ICP-MS.Journal of analytical atomic spectrometry · 2026Article
- Iron need attention: a review on the role of iron in plants.Frontiers in plant science · 2026Review
- AhMTP9-Mediated manganese tolerance mechanisms in peanut: integrated physiological and molecular responses of roots and leaves to Mn stress.BMC plant biology · 2025Article
- Time-Series Elemental Imaging Reveals CAX-Dependent Redistribution Patterns for Anoxia Recovery.Journal of experimental botany · 2025Article
- NnMTP10 from Nelumbo nucifera acts as a transporter mediating manganese and iron efflux.Plant molecular biology · 2025Article
- Manganese handling in plants: Advances in the mechanistic and functional understanding of transport pathways.Quantitative plant biology · 2025Review
- Genomic characterisation of the metal tolerance protein gene family and elucidation of functional role in heavy metal tolerance and accumulation inFrontiers in plant science · 2025Article
- Ion toxicity in waterlogged soils: mechanisms of root response and adaptive strategies.Frontiers in plant science · 2025Review
- Arabidopsis MEB3 functions as a vacuolar metal transporter to regulate iron accumulation in roots.Frontiers in plant science · 2025Article
- Deciphering the functional roles of transporter proteins in subcellular metal transportation of plants.Planta · 2023Review
- Cell type-specific mapping of ion distribution in Arabidopsis thaliana roots.Nature communications · 2023Article
- Dissecting the relative contribution of ECA3 and group 8/9 cation diffusion facilitators to manganese homeostasis inPlant direct · 2023Article
- Fast X-ray fluorescence microscopy provides high-throughput phenotyping of element distribution in seeds.Plant physiology · 2023Article
- Biofortification of common bean (Food and energy security · 2023Review
- Comprehensive Survey of ChIP-Seq Datasets to Identify Candidate Iron Homeostasis Genes Regulated by Chromatin Modifications.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Black sheep, dark horses, and colorful dogs: a review on the current state of the Gene Ontology with respect to iron homeostasis inFrontiers in plant science · 2023Review
- A metal tolerance protein, MTP10, is required for the calcium and magnesium homeostasis inPlant signaling & behavior · 2022Article
- Effect of Light Quality on Metabolomic, Ionomic, and Transcriptomic Profiles in Tomato Fruit.International journal of molecular sciences · 2022Article
- Quantitative imaging approaches to understanding biological processing of metal ions.Current opinion in chemical biology · 2022Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Understanding how seeds obtain and store nutrients is key to developing crops with higher agronomic and nutritional value. We have uncovered unique patterns of micronutrient localization in seeds using synchrotron X-ray fluorescence (SXRF). Although all four members of the Arabidopsis thaliana Mn-CDF family can transport Mn, here we show that only mtp8-2 has an altered Mn distribution pattern in seeds. In an mtp8-2 mutant, Mn no longer accumulates in hypocotyl cortex cells and sub-epidermal cells of the embryonic cotyledons, but rather accumulates with Fe in the cells surrounding the vasculature, a pattern previously shown to be determined by the vacuolar transporter VIT1. We also show that MTP8, unlike the other three Mn-CDF family members, can transport Fe and is responsible for localization of Fe to the same cells that store Mn. When both the VIT1 and MTP8 transporters are non-functional, there is no accumulation of Fe or Mn in specific cell types; rather these elements are distributed amongst all cell types in the seed. Disruption of the putative Fe binding sites in MTP8 resulted in loss of ability to transport Fe but did not affect the ability to transport Mn.
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