Evidence map›Paper›PMID 28887536›Full record

ArticleScientific reports2017

Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe

Poorani Krishnan, Mariappan Rajan, Sharmilah Kumari, S Sakinah, Sivan Padma Priya, Fatin Amira, Lawal Danjuma, Mok Pooi Ling, Sharida Fakurazi, Palanisamy Arulselvan and 8 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Camptothecin Encapsulated in β-Cyclodextrin-EDTA-FeNanomaterials (Basel, Switzerland) · 2021
    Article
  10. Article
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  12. Article
  13. Article
  14. Article
  15. Review
  16. The impact of camptothecin-encapsulated poly(lactic-International journal of nanomedicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 6 countries.

Poorani KrishnanDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Mariappan RajanDepartment of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625 021, Tamil Nadu, India. rajanm153@gmail.com.ORCID 0000-0001-9569-8744
Sharmilah KumariDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
S SakinahDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Sivan Padma PriyaDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Fatin AmiraDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Lawal DanjumaDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Mok Pooi LingDepartment of Biomedical Science, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Sharida FakuraziLaboratory of Vaccines and Immunotherapeutic, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Palanisamy ArulselvanLaboratory of Vaccines and Immunotherapeutic, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.
Akon HiguchiDepartment of Chemical and Materials Engineering, National Central University, Jhong-li, Taoyuan, 32001, Taiwan.ORCID 0000-0003-2970-8531
Ramitha ArumugamDepartment of Biology, Faculty of Science, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
Abdullah A AlarfajDepartment of Botany and Microbiology, King Saud University, Riyadh, 11451, Saudi Arabia.
Murugan A MunusamyDepartment of Botany and Microbiology, King Saud University, Riyadh, 11451, Saudi Arabia.
Rukman Awang HamatDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia.ORCID 0000-0001-6288-3791
Giovanni BenelliDepartment of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124, Pisa, Italy.
Kadarkarai MuruganDivision of Entomology, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, Tamil Nadu, India.
S Suresh KumarDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM, Serdang Selangor, Malaysia. sureshkudsc@gmail.com.
Universiti Putra Malaysia · MYKing Saud University · SABharathiar University · INMadurai Kamaraj University · INNational Central University · TWUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE

Indexed as

Antineoplastic Agents, PhytogenicApoptosisbeta-CyclodextrinsCamptothecinColonic NeoplasmsEdetic AcidFerric CompoundsG1 PhaseHT29 CellsHumansNanoconjugatesAntineoplastic Agents, Phytogenicbeta-CyclodextrinsbetadexCamptothecinEdetic AcidFerric Compoundsferric oxideNanoconjugates

Identifiers

PMID28887536
PMCPMC5591276
OpenAlexW2753452553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.