ArticleStroke2017
White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke.
Article in Stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of leukoaraiosis severity on the association of outcomes of mechanical thrombectomy for acute ischemic stroke: a systematic review and a meta-analysis.Journal of neurology · 2021Pooled it
- Small Vessel Disease Burden and Outcomes of Mechanical Thrombectomy in Ischemic Stroke: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- CT Radiomic Features of the Crystalline Lens and Association with Age, Hypertension and Cerebral White Matter Lesions.Diagnostics (Basel, Switzerland) · 2026Article
- Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke.Neurological research and practice · 2025Article
- Brain Frailty on Neuroimaging Beyond Chronological Age Is Associated with Functional Outcome After Endovascular Thrombectomy in Patients with Anterior Large Vessel Occlusion.Therapeutics and clinical risk management · 2025Article
- Association between periventricular hyperintensity or deep white matter hyperintensity and outcomes of patients with ischemic stroke.Frontiers in neurology · 2025Article
- The impact of white matter hyperintensities on short-term outcomes of reperfusion therapy in patients with acute ischemic stroke.Journal of neurology · 2024Article
- Impact of White Matter Hyperintensity Volume on Prognosis After Mechanical Thrombectomy in Ischemic Stroke Patients.Stroke (Hoboken, N.J.) · 2024Article
- Article
- Cerebral Small Vessel Disease and Outcomes in Patients With Acute Ischemic Stroke Receiving Endovascular Treatment: A Systematic Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2023Article
- Association between Citrullinated Histone H3 and White Matter Lesions Burden in Patients with Ischemic Stroke.Brain sciences · 2023Article
- Elucidating the Role of Baseline Leukoaraiosis on Forecasting Clinical Outcome of Acute Ischemic Stroke Patients Undergoing Reperfusion Therapy.Neurology international · 2022Review
- Efficacy of intravenous thrombolysis combined with mechanical stent interventional thrombectomy on acute ischemic stroke.Journal of medical biochemistry · 2022Article
- Small vessel disease and collaterals in ischemic stroke patients treated with thrombectomy.Journal of neurology · 2022Article
- Effect of Cerebral Small Vessel Disease Burden on Outcomes in Patients With Acute Ischemic Stroke Receiving Endovascular Treatment.Frontiers in aging neuroscience · 2022Article
- White Matter Acute Infarct Volume After Thrombectomy for Anterior Circulation Large Vessel Occlusion Stroke is Associated with Long Term Outcomes.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Article
- Article
- Relationship of white matter lesion severity with early and late outcomes after mechanical thrombectomy for large vessel stroke.Journal of neurointerventional surgery · 2021Article
- White Matter Disease and Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2020Article
- White matter burden does not influence the outcome of mechanical thrombectomy.Journal of neurology · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
background and purposeFinding of white matter hyperintensity (WMH) has been associated with an increased risk of parenchymal hematoma and poor clinical outcomes after mechanical thrombectomy using old-generation endovascular devices. Currently, no data exist with regard to the risk of mechanical thrombectomy using stentriever devices in patients with significant WMH. We hypothesized that WMH volume will not affect the hemorrhagic and clinical outcome in patients with acute ischemic stroke undergoing thrombectomy using new-generation devices.
methodsA retrospective cohort of consecutive acute ischemic stroke patients >18-year-old receiving mechanical thrombectomy with stentriever devices at a single academic center was examined. WMH volume was assessed by a semiautomated volumetric analysis on T2 fluid attenuated inversion recovery-magnetic resonance imaging. Outcomes included the rate of any intracerebral hemorrhage, 90-day modified Rankin Score (mRS), the rate of good outcome (discharge mRS ≤2), and the rate of successful reperfusion (thrombolysis in cerebral ischemia score 2b or 3).
resultsBetween June 2012 and December 2015, 56 patients with acute ischemic stroke met the study criteria. Median WMH volume was 6.76 cm
conclusionsMechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
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