Evidence map›Paper›PMID 28887053›Full record

ArticleContraception2018

Modeling the impact of novel male contraceptive methods on reductions in unintended pregnancies in Nigeria, South Africa, and the United States.

Emily Dorman, Brian Perry, Chelsea B Polis, Lisa Campo-Engelstein, Dominick Shattuck, Aaron Hamlin, Abigail Aiken, James Trussell, David Sokal

Open access · greenAbstract read
In one paragraph

Article in Contraception, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Hormonal Male Contraception: Getting to Market.Frontiers in endocrinology · 2022
    Article
  8. Update on Novel Hormonal and Nonhormonal Male Contraceptive Development.The Journal of clinical endocrinology and metabolism · 2021
    Review
  9. Article
  10. Male Contraception.The Yale journal of biology and medicine · 2020
    Review
  11. The future of male contraception: a fertile ground.Translational andrology and urology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Emily DormanModeling and Simulation, Evidera Inc., Bethesda, MD, USA; Male Contraception Initiative, Durham, NC, USA.
Brian PerryDepartment of Population Health Science, Duke University, Durham, NC, USA. Electronic address: brian.perry@duke.edu.
Chelsea B PolisDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Guttmacher Institute, New York, NY, USA.
Lisa Campo-EngelsteinAlden March Bioethics Institute and Department of Obstetrics and Gynecology, Albany Medical College, Albany, NY, USA.
Dominick ShattuckInstitute for Reproductive Health, Georgetown University, Washington, DC, USA.
Aaron HamlinMale Contraception Initiative, Durham, NC, USA.
Abigail AikenLBJ School of Public Affairs, University of Texas at Austin, Austin, TX, USA.
James TrussellOffice of Population Research, Princeton University, Princeton, NJ, USA; University of Edinburgh, Edinburgh, Scotland.
David SokalMale Contraception Initiative, Durham, NC, USA; Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Albany Medical Center Hospital · USDuke University · USGeorgetown University · USGuttmacher Institute · USPrinceton University · USThe University of Texas at Austin · USUniversity of North Carolina at Chapel Hill · USU.S. President's Malaria Initiative · US

Funding

Infrastructure for Population Research at PrincetonR24HD047879 · NICHD · PRINCETON UNIVERSITY · PI MASSEY, DOUGLAS S · 2004 to 2013
$7.3M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
NICHD NIH HHS P2C HD042849NICHD NIH HHS P2C HD047879NICHD NIH HHS R24 HD047879
6 · The paper itself

Abstract

objectiveWe modeled the potential impact of novel male contraceptive methods on averting unintended pregnancies in the United States, South Africa, and Nigeria. STUDY

designWe used an established methodology for calculating the number of couple-years of protection provided by a given contraceptive method mix. We compared a "current scenario" (reflecting current use of existing methods in each country) against "future scenarios," (reflecting whether a male oral pill or a reversible vas occlusion was introduced) in order to estimate the impact on unintended pregnancies averted. Where possible, we based our assumptions on acceptability data from studies on uptake of novel male contraceptive methods.

resultsAssuming that only 10% of interested men would take up a novel male method and that users would comprise both switchers (from existing methods) and brand-new users of contraception, the model estimated that introducing the male pill or reversible vas occlusion would decrease unintended pregnancies by 3.5% to 5.2% in the United States, by 3.2% to 5% in South Africa, and by 30.4% to 38% in Nigeria. Alternative model scenarios are presented assuming uptake as high as 15% and as low as 5% in each location. Model results were sensitive to assumptions regarding novel method uptake and proportion of switchers vs. new users.

conclusionEven under conservative assumptions, the introduction of a male pill or temporary vas occlusion could meaningfully contribute to averting unintended pregnancies in a variety of contexts, especially in settings where current use of contraception is low. IMPLICATIONS: Novel male contraceptives could play a meaningful role in averting unintended pregnancies in a variety of contexts. The potential impact is especially great in settings where current use of contraception is low and if novel methods can attract new contraceptive users.

Indexed as

ContraceptionModels, TheoreticalPregnancy RatePregnancy, UnplannedFemaleHumansMaleNigeriaPregnancySouth AfricaUnited StatesCYPMale contraceptionMale pillMathematical modelReversible vas occlusionUnintended pregnancy

Identifiers

PMID28887053
PMCPMC5732079
OpenAlexW2751560763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.