Evidence map›Paper›PMID 28886701›Full record

ArticleBMC neuroscience2017

The loss-of-function disease-mutation G301R in the Na

Ditte Gry Ellman, Toke Jost Isaksen, Minna Christiansen Lund, Safinaz Dursun, Martin Wirenfeldt, Louise Helskov Jørgensen, Karin Lykke-Hartmann, Kate Lykke Lambertsen

Open access · goldAbstract read
In one paragraph

Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Forced polarisation of microglia by IL-13 is modified by inflammatory and microenvironmental context.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  3. New Diagnostic and Therapeutic Targets for Spinal Cord Injury: GRN Gene.Journal of cellular and molecular medicine · 2025
    Article
  4. Review
  5. NaBiomedicines · 2023
    Review
  6. Article
  7. Review
  8. The αScientific reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ditte Gry EllmanNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense C, Denmark.
Toke Jost IsaksenDepartment of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark.
Minna Christiansen LundNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense C, Denmark.
Safinaz DursunNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense C, Denmark.
Martin WirenfeldtDepartment of Pathology, University of Southern Denmark/Odense University Hospital, Odense, 5000, Odense C, Denmark.
Louise Helskov JørgensenDepartment of Pathology, University of Southern Denmark/Odense University Hospital, Odense, 5000, Odense C, Denmark.
Karin Lykke-HartmannDepartment of Biomedicine, Aarhus University, 8000, Aarhus C, Denmark. kly@biomed.au.dk.ORCID 0000-0002-6702-183X
Kate Lykke LambertsenNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, 5000, Odense C, Denmark. klambertsen@health.sdu.dk.
University of Southern Denmark · DKAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Na

resultsWe found that α

conclusionOur proof of concept study demonstrates that reduced expression of the α

Indexed as

AnimalsCell MembraneGenotypeInterleukin-10IsoenzymesMembrane PotentialsMice, TransgenicMutationRecovery of FunctionSignal TransductionSodium-Potassium-Exchanging ATPaseSpinal Cord InjuriesAtp1a2 protein, mouseInterleukin-10IsoenzymesSodium-Potassium-Exchanging ATPaseFunctional recoveryNa+/K+-ATPase α2 isoformReduced lesion volumeSpinal cord injury

Identifiers

PMID28886701
PMCPMC5590116
OpenAlexW2751601765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.