Evidence map›Paper›PMID 28886499›Full record

ArticleJournal of affective disorders2018

Increased reward-oriented impulsivity in older bipolar patients: A preliminary study.

Isabelle E Bauer, Breno Satler Diniz, Thomas D Meyer, Antonio Lucio Teixeira, Marsal Sanches, Danielle Spiker, Giovana Zunta-Soares, Jair C Soares

Abstract read
In one paragraph

Article in Journal of affective disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review of Emotion Regulation in Late Life Mood Disorders.Journal of psychiatry and brain science · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabelle E BauerUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States. Electronic address: Isabelle.E.Bauer@uth.tmc.edu.
Breno Satler DinizUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.
Thomas D MeyerUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.
Antonio Lucio TeixeiraUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.
Marsal SanchesUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States; Archway Mental Health Services, 58502 Bismarck, ND, United States.
Danielle SpikerUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.
Giovana Zunta-SoaresUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.
Jair C SoaresUniversity of Texas Health Science Center at Houston, McGovern Medical School, Department of Psychiatry and Behavioral Sciences, 77054 Houston, TX, United States.

Funding

Searching for Endophenotypes of Bipolar DisorderR01MH085667 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SOARES, JAIR C · 2012 to 2016
$3.0M
NIMH NIH HHS R01 MH085667
6 · The paper itself

Abstract

objectiveImpulsivity is a well-established trait of bipolar disorder (BD) that persists across mood phases. It is, however, still unknown whether, in BD, impulsivity remains stable or varies in intensity over the lifespan. This cross-sectional study compared impulsive behavior in older euthymic BD patients and healthy individuals using a range of self-rating and behavioral measures of impulsivity.

methods28 BD patients (56.07 ± 4.08 years, 16 women) and 15 healthy controls (HC; 55.1 ± 3.95 years, 6 women) were administered the Barratt Impulsivity Scale (BIS) and selected tasks of the Cambridge Neuropsychological Test Automated Batter (CANTAB) reflecting impulsivity. Multivariate analysis of variance controlled for age compared impulsivity measures across BD and HC.

resultsBD patients displayed poor decision making, risk taking, and increased delay aversion. Other measures of impulsivity such as response inhibition, sustained cognitive control, and BIS scores were, overall, comparable between BD and HC.

conclusionsThese preliminary findings suggest that, in BD, aspects of impulsivity related to reward-based decision making persist into late adulthood. Large scale, longitudinal studies are needed to evaluate the relationship of age to impulsivity over time, and explore the link between impulsivity and illness progression in elderly individuals with BD.

Indexed as

RewardAdultAffectAgedAnalysis of VarianceBipolar DisorderCross-Sectional StudiesCyclothymic DisorderDecision MakingDisease ProgressionFemaleHumansImpulsive BehaviorMaleMiddle AgedNeuropsychological TestsBipolar disorderCognitive controlImpulsivityOld ageReward

Identifiers

PMID28886499
PMCPMC5626658

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.