Evidence map›Paper›PMID 28886217›Full record

ArticleBiometrics2018

Analysis of restricted mean survival time for length-biased data.

Chi Hyun Lee, Jing Ning, Yu Shen

Abstract read
In one paragraph

Article in Biometrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. A technique for approximating transition rates from published survival analyses.Cost effectiveness and resource allocation : C/E · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chi Hyun LeeDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, U.S.A.ORCID 0000-0001-6340-2718
Jing NingDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, U.S.A.
Yu ShenDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, U.S.A.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Comparative Effectiveness of Cancer Research: Use Data from Multiple SourcesR01CA193878 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI NING, JING · 2016 to 2019
$1.2M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA193878
6 · The paper itself

Abstract

In clinical studies with time-to-event outcomes, the restricted mean survival time (RMST) has attracted substantial attention as a summary measurement for its straightforward clinical interpretation. When the data are subject to length-biased sampling, which is frequently encountered in observational cohort studies, existing methods to estimate the RMST are not applicable. In this article, we consider nonparametric and semiparametric regression methods to estimate the RMST under the setting of length-biased sampling. To assess the covariate effects on the RMST, a semiparametric regression model that directly relates the covariates and the RMST is assumed. Based on the model, we develop unbiased estimating equations to obtain consistent estimators of covariate effects by properly adjusting for informative censoring and length bias. Stochastic process theories are used to establish the asymptotic properties of the proposed estimators. We investigate the finite sample performance through simulations and illustrate the methods by analyzing a prevalent cohort study of dementia in Canada.

Indexed as

Data Interpretation, StatisticalSurvival AnalysisCanadaCohort StudiesComputer SimulationDementiaRegression AnalysisSelection BiasStochastic ProcessesLength-biased dataNonparametric estimationRestricted mean survival timeSemiparametric regression method

Identifiers

PMID28886217
PMCPMC5843504

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.