ArticlePloS one2017
Associations between lower-limb muscle activation and knee flexion in post-stroke individuals: A study on the stance-to-swing phases of gait.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Changes in leg cycling muscle synergies after training augmented by functional electrical stimulation in subacute stroke survivors: a pilot study.Journal of neuroengineering and rehabilitation · 2020Trial
- Relationship between lower limb muscle coordination and knee flexion angle during the swing phase of gait in post-stroke individuals.Journal of neuroengineering and rehabilitation · 2026Article
- Article
- Task-Based Mapping of Compensatory Strategies and Movement Kinematics After Stroke: A Systematic Scoping Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Effects of Robot-Assisted Gait Training on Stage-Based Lower Limb Motor Recovery and Muscle Tone in Subacute Stroke: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Unveiling the hidden dynamics: patellar support tissue alterations in post-stroke rehabilitation.Frontiers in rehabilitation sciences · 2026Article
- The Effects of Functional Electrical Stimulation of Hip Abductor and Tibialis Anterior Muscles on Standing and Gait Characteristics in Patients with Stroke.Journal of clinical medicine · 2025Article
- Article
- Gait analysis system for assessing abnormal patterns in individuals with hemiparetic stroke during robot-assisted gait training: a criterion-related validity study in healthy adults.Frontiers in neurorobotics · 2025Article
- A Linear Rehabilitative Motion Planning Method with a Multi-Posture Lower-Limb Rehabilitation Robot.Sensors (Basel, Switzerland) · 2024Article
- Early screening of post-stroke fall risk: A simultaneous multimodal fNIRs-EMG study.CNS neuroscience & therapeutics · 2024Article
- Comparative electromyography analysis of subphase gait disorder in chronic stroke survivors.PeerJ · 2024Article
- Altered biomechanical strategies of the paretic hip and knee joints during a step-up task.Topics in stroke rehabilitation · 2023Article
- Case report: A novel approach of closed-loop brain stimulation combined with robot gait training in post-stroke gait disturbance.Frontiers in human neuroscience · 2023Article
- Recent Trends and Practices Toward Assessment and Rehabilitation of Neurodegenerative Disorders: Insights From Human Gait.Frontiers in neuroscience · 2022Review
- Necessity and Content of Swing Phase Gait Coordination Training Post Stroke; A Case Report.Brain sciences · 2021Article
- Effect of Leg Extension Angle on Knee Flexion Angle during Swing Phase in Post-Stroke Gait.Medicina (Kaunas, Lithuania) · 2021Article
- Dynamical Analysis of Standing Balance Control on Sloped Surfaces in Individuals with Lumbar Disc Herniation.Scientific reports · 2020Article
- Effect of Functional Electrical Stimulation of the Gluteus Medius during Gait in Patients following a Stroke.BioMed research international · 2020Article
- Co-Contraction of Lower Limb Muscles Contributes to Knee Stability During Stance Phase in Hemiplegic Stroke Patients.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reduced knee flexion is a leading feature of post-stroke gait, but the causes have not been well understood. The purpose of this study was to investigate the relationship between the knee flexion and the lower-limb muscle activation within the stance-to-swing phases of gait cycle in the post-stroke hemiplegic patients. Ten stroke patients and 10 age- and gender-matched healthy subjects participated in the experiment. The lower-limb kinematic signals and the surface electromyography (sEMG) signals of the left and right rectus femoris (RF), biceps femoris (BF) and lateral gastrocnemius (GS) were recorded during walking. The angle range (AR) of knee flexion, the root mean square (RMS) and the mean frequency (MNF) of sEMG signals were calculated from the terminal stance (TSt) to the initial swing (ISw) phases of gait cycle. Stroke patients showed lower bilateral AR of knee flexion and lower RMS of GS on the paretic side, but higher MNF of RF on the non-paretic side compared with the controls. Within the stroke patients, significant differences were found between their paretic and non-paretic limbs in the AR of knee flexion, as well as in the RMS and MNF of GS (p < 0.05). Regression analysis showed that the RMS of BF, MNF of BF and MNF of GS explained 82.1% of variations in AR of knee flexion on paretic side (r2 = 0.821). But the RMS and MNF of all the muscles (including the RF, GS and BF) could explain 65.6% of AR of knee flexion variations on the non-paretic side (r2 = 0.656), and 45.2% of variations for the healthy subjects (r2 = 0.452). The reduced knee flexion during gait was associated with altered magnitude and frequency of muscle contractions and with simplified muscle synergy in the post-stroke hemiplegic patients. Identifying the muscles that are responsible for knee stiffness may facilitate improvement of rehabilitation strategy for post-stroke gait.
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