ArticlePloS one2017
Dynamics of the aortic annulus in 4D CT angiography for transcatheter aortic valve implantation patients.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Impact of left ventricular inflow-outflow angle on heart failure readmission post-transcatheter aortic valve implantation.The international journal of cardiovascular imaging · 2024Article
- Impact of sigmoid septum on periprocedural outcomes following transcatheter aortic valve implantation using current-generation valves.The international journal of cardiovascular imaging · 2022Article
- A Patient-Specific 3Dt Coronary Artery Motion Modeling Method Using Hierarchical Deformation with ElectrocardiogramSensors (Basel, Switzerland) · 2020Article
- Are the dynamic changes of the aortic root determinant for thrombosis or leaflet degeneration after transcatheter aortic valve replacement?Journal of thoracic disease · 2020Review
- A left ventricular lead implantation at the latest site based on four-dimensional computed tomography: a case report.European heart journal. Case reports · 2020Article
- A case of a low-displacement area on four-dimensional computed tomography corresponding to a low-voltage area on the voltage map.HeartRhythm case reports · 2020Article
- Assessment of aortic valve tract dynamics using automatic tracking of 3D transesophageal echocardiographic images.The international journal of cardiovascular imaging · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscatheter aortic valve implantation (TAVI) is a well-established treatment for patients with severe aortic valve stenosis. This procedure requires pre-operative planning by assessment of aortic dimensions on CT Angiography (CTA). It is well-known that the aortic root dimensions vary over the heart cycle. However, sizing is commonly performed at either mid-systole or end-diastole only, which has resulted in an inadequate understanding of its full dynamic behavior. STUDY GOAL: We studied the variation in annulus measurements during the cardiac cycle and determined if this variation is dependent on the amount of calcification at the annulus.
methodsWe measured and compared aortic root annular dimensions and calcium volume in CTA acquisitions at 10 cardiac cycle phases in 51 aortic stenosis patients. Sub-group analysis was performed based on the volume of calcium by splitting the population into mildly and severely calcified valves subgroups.
resultsFor most annulus measurements, the largest differences were found between 10% and 70 to 80% cardiac cycle phases. Mean difference (±standard deviation) in annular minimum diameter, maximum diameter, area, and aspect ratio between mid-systole and end-diastole phases were 1.0 ± 0.29 mm (p = 0.065), 0.30 ± 0.24 mm (p = 0.7), 24.1 ± 7.6 mm2 (p < 0.001), and 0.041 ± 0.012 (p = 0.039) respectively. Calcium volume measurements varied strongly during the cardiac cycle. The dynamic annulus area was behaving differently between mildly and severely calcified subgroups (p = 0.02). Furthermore, patients with severe aortic calcification were associated with larger annulus diameters.
conclusionThere is a significant variation of annulus area and calcium volume measurement during the cardiac cycle. In our measurements, only the dynamic variation of the annulus area is dependent on the severity of the aortic calcification. For TAVI candidates, the annulus area is significantly larger in mid-systole compared to end-diastole.
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