Evidence map›Paper›PMID 28885922›Full record

ArticleMilitary medicine2017

Management of Acute Diarrheal Illness During Deployment: A Deployment Health Guideline and Expert Panel Report.

Mark S Riddle, Gregory J Martin, Clinton K Murray, Timothy H Burgess, Patrick Connor, James D Mancuso, Elizabeth R Schnaubelt, Timothy P Ballard, Jamie Fraser, David R Tribble

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Military medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07272122 (Reducing Filth Fly Populations and Transmission of Diarrhoeal Pathogens in Harsh Settings), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07272122 phase3recruitingnot on this mapstarted 2026, after this paper: background citation

Reducing Filth Fly Populations and Transmission of Diarrhoeal Pathogens in Harsh Settings: a Cross-over Trial in South Sudan

TypeinterventionalSponsorThe Mentor InitiativeRan2026 to 2027Enrolled5,556ConditionsDiarrheal DiseasesArmsBaited fly traps - iCatchi® ProMax fly traps, Insect growth regulator (IGR) - effervescent granule containing 2% diflubenzuron (20g/kg)
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Shigellosis.Lancet (London, England) · 2025
    Review
  4. Article
  5. Sharing ofmBio · 2025
    Article
  6. Article
  7. Outbreak of Diarrhea Caused by a NovelOpen forum infectious diseases · 2024
    Article
  8. Frontiers in nutrition · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Antibiotic Resistance ofAntimicrobial agents and chemotherapy · 2019
    Article
  16. Article
  17. Review
  18. IntestinalFrontiers in physiology · 2018
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Mark S RiddleEnteric Disease Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910.
Gregory J MartinChief, Tropical Medicine-Infectious Diseases, Bureau of Medical Services, U.S. Department of State, 2401 E Street NW L209, Washington, DC 20037.
Clinton K MurrayDeputy Medical Corps, Chief, Medical Corps Specific Branch Proponent Officer, Infectious Disease Consultant to the Army Surgeon General, Brooke Army Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, TX 78234.
Timothy H BurgessInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.
Patrick ConnorMilitary Enteric Disease Group, Academic Department of Military Medicine, Birmingham Research Park, Vincent Drive, Birmingham B15 2SQ, United Kingdom.
James D MancusoDepartment of Preventive Medicine & Biostatistics, The F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.
Elizabeth R SchnaubeltInfectious Disease Service, Landstuhl Regional Medical Center, Landstuhl, Germany, CMR 402, APO, AE, 19180. (Current Affiliation: Division of Global HIV and TB, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA).
Timothy P BallardOperational Medicine, Defense Institute for Medical Operations, 1320 Truemper Street, Building 9122, JBSA-Lackland, TX 78236.
Jamie FraserInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.
David R TribbleInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.
Uniformed Services University of the Health Sciences · US59th Medical Wing · USBirmingham Research Park · GBHenry M. Jackson Foundation · USLandstuhl Regional Medical Center · DENaval Medical Research Command · USUnited States Department of State · USUnited States Department of the Army · US

Funding

DATA CENTER FOR EPIDEMIOLOGIC INVESTIGATIONS OF HIVN01AI005072 · NIAID · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1990 to 1994
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NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

backgroundAcute diarrheal illness during deployment causes significant morbidity and loss of duty days. Effective and timely treatment is needed to reduce individual, unit, and health system performance impacts.

methodsThis critical appraisal of the literature, as part of the development of expert consensus guidelines, asked several key questions related to self-care and healthcare-seeking behavior, antibiotics for self-treatment of travelers' diarrhea, what antibiotics/regimens should be considered for treatment of acute watery diarrhea and febrile diarrhea and/or dysentery, and when and what laboratory diagnostics should be used to support management of deployment-related travelers' diarrhea. Studies of acute diarrhea management in military and other travelers were assessed for relevance and quality. On the basis of this critical appraisal, guideline recommendations were developed and graded by the Expert Panel using good standards in clinical guideline development methodology.

resultsNew definitions for defining the severity of diarrhea during deployment were established. A total of 13 graded recommendations on the topics of prophylaxis, therapy and diagnosis, and follow-up were developed. In addition, four non-graded consensus-based statements were adopted.

conclusionsSuccessful management of acute diarrheal illness during deployment requires action at the provider, population, and commander levels. Strong evidence supports that single-dose antimicrobial therapy is effective in most cases of moderate to severe acute diarrheal illness during deployment. Further studies are needed to address gaps in available knowledge regarding optimal therapies for treatment, prevention, and laboratory testing of acute diarrheal illness.

Indexed as

Disease ManagementDiarrheaDisease OutbreaksEvidence-Based MedicineGuidelines as TopicHumansWarfare

Identifiers

PMID28885922
PMCPMC5657341
OpenAlexW2751330553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.