ArticleThe ISME journal2018
Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs.
Article in The ISME journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 50 citations in OpenAlex.
- Post mortem laboratory detection of Helicobacter spp. in swine.Veterinary research communications · 2025Article
- Cross-species single-cell transcriptomic analysis of animal gastric antrum reveals intense porcine mucosal immunity.Cell regeneration (London, England) · 2023Article
- Development of serological assays to identifyiScience · 2023Article
- Perception and Knowledge of Portuguese Veterinarians about the Zoonotic Transmission ofInternational journal of environmental research and public health · 2022Article
- Molecular detection of Helicobacter spp. and Fusobacterium gastrosuis in pigs and wild boars and its association with gastric histopathological alterations.Veterinary research · 2022Article
- Gastric Helicobacter species associated with dogs, cats and pigs: significance for public and animal health.Veterinary research · 2022Review
- Antibiotic resistance pattern and frequency of cagA and vacA genes in Helicobacter pylori strains isolated from patients in Tabriz city, Iran.BMC research notes · 2021Article
- Presence ofAnimals : an open access journal from MDPI · 2021Article
- First report of PCR-based detection ofVeterinary world · 2020Article
- Distinct transcriptome signatures of Helicobacter suis and Helicobacter heilmannii strains upon adherence to human gastric epithelial cells.Veterinary research · 2020Article
- Article
- Macroevolution of gastric Helicobacter species unveils interspecies admixture and time of divergence.The ISME journal · 2018Article
Corrections and comments
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Authors and funding
33 authors at 18 institutions in 14 countries.
Funding
Abstract
Helicobacter suis is the second most prevalent Helicobacter species in the stomach of humans suffering from gastric disease. This bacterium mainly inhabits the stomach of domesticated pigs, in which it causes gastric disease, but it appears to be absent in wild boars. Interestingly, it also colonizes the stomach of asymptomatic rhesus and cynomolgus monkeys. The origin of modern human-, pig- or non-human primate-associated H. suis strains in these respective host populations was hitherto unknown. Here we show that H. suis in pigs possibly originates from non-human primates. Our data suggest that a host jump from macaques to pigs happened between 100 000 and 15 000 years ago and that pig domestication has had a significant impact on the spread of H. suis in the pig population, from where this pathogen occasionally infects humans. Thus, in contrast to our expectations, H. suis appears to have evolved in its main host in a completely different way than its close relative Helicobacter pylori in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.