Evidence map›Paper›PMID 28885620›Full record

ArticleCell death and differentiation2017

Oxidative stress-induced S100B accumulation converts myoblasts into brown adipocytes via an NF-κB/YY1/miR-133 axis and NF-κB/YY1/BMP-7 axis.

Giulio Morozzi, Sara Beccafico, Roberta Bianchi, Francesca Riuzzi, Ilaria Bellezza, Ileana Giambanco, Cataldo Arcuri, Alba Minelli, Rosario Donato

Open access · bronzeAbstract read
In one paragraph

Article in Cell death and differentiation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  7. Tissue-Specific Expression of the PorcineAnimals : an open access journal from MDPI · 2025
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  8. Spotlight on the Mechanism of Action of Semaglutide.Current issues in molecular biology · 2024
    Review
  9. Article
  10. Review
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  13. Article
  14. Article
  15. Review
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  17. Article
  18. Biological Aspects of Selected Myokines in Skeletal Muscle: Focus on Aging.International journal of molecular sciences · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giulio MorozziDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Sara BeccaficoDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Roberta BianchiDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Francesca RiuzziDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Ilaria BellezzaDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Ileana GiambancoDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Cataldo ArcuriDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Alba MinelliDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
Rosario DonatoDepartment of Experimental Medicine, Istituto Interuniversitario di Miologia, Perugia Medical School, University of Perugia, Perugia, Italy.
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscles of sarcopenic people show hypotrophic myofibers and infiltration with adipose and, at later stages, fibrotic tissue. The origin of infiltrating adipocytes resides in fibro-adipogenic precursors and nonmyogenic mesenchymal progenitor cells, and in satellite cells, the adult stem cells of skeletal muscles. Myoblasts and brown adipocytes share a common Myf5

Indexed as

Adipocytes, BrownAnimalsBone Morphogenetic Protein 7HumansMaleMiceMicroRNAsMyoblastsNF-kappa BOxidative StressReactive Oxygen SpeciesS100 Calcium Binding Protein beta SubunitTransfectionYY1 Transcription FactorBone Morphogenetic Protein 7MicroRNAsNF-kappa BReactive Oxygen SpeciesS100 Calcium Binding Protein beta SubunitYY1 Transcription Factor

Identifiers

PMID28885620
PMCPMC5686349
OpenAlexW2750887238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.