Evidence map›Paper›PMID 28885600›Full record

ArticleNutrients2017

A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults.

Daniel Cummings, Kevin F Dowling, Noah J Silverstein, Alexandra S Tanner, Hamdi Eryilmaz, Jordan W Smoller, Joshua L Roffman

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel CummingsDepartment of Biopsychology, Tufts University, 419 Boston Ave, Medford, MA 02155, USA. daniel.cummings1@gmail.com.
Kevin F DowlingDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. kfdowling@mgh.harvard.edu.ORCID 0000-0001-5609-7727
Noah J SilversteinDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. noah.silverstein@umassmed.edu.
Alexandra S TannerDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. alexandra.s.tanner@gmail.com.
Hamdi EryilmazDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. hamdi.eryilmaz@mgh.harvard.edu.
Jordan W SmollerDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. jsmoller@partners.org.
Joshua L RoffmanDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA. jroffman@partners.org.
Harvard University · USTufts University · US

Funding

MRI Studies of Folate-Related Genes, Diet, and Development: Promise for PsychosisR01MH101425 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ROFFMAN, JOSHUA LAWRENCE · 2013 to 2017
$2.8M
NIMH NIH HHS R01 MH101425
6 · The paper itself

Abstract

Since 1998, the U.S. has mandated folic acid (FA) fortification of certain grain products to reduce the risk of neural tube defects. Folate intake and red blood cell (RBC) folate concentrations increased substantially post-intervention, although recent studies raise concerns about the level of ongoing benefit. This study investigated blood folate level determinants in healthy young adults, including intake of naturally occurring food folate, synthetic FA, and the interaction of naturally occurring food folate with a common missense variant in the

Indexed as

DietAdolescentAdultCross-Sectional StudiesDietary SupplementsFemaleFolic AcidFolic Acid DeficiencyFood, FortifiedHumansMaleNutritional RequirementsNutritional StatusYoung AdultFolic Aciddietary folateFOLH1folic acidRBC folate

Identifiers

PMID28885600
PMCPMC5622754
OpenAlexW2751789498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.