ArticleTransplantation2018
Prevalence and Predictors of Patient-Reported Long-term Mental and Physical Health After Donation in the Adult-to-Adult Living-Donor Liver Transplantation Cohort Study.
Article in Transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The long-term follow-up of the living liver donors.Updates in surgery · 2025Pooled it
- PRehab tO PreparE Living Liver Donors for Enhanced Recovery (PROPELLER): A Feasibility Randomized Controlled Trial.Clinical transplantation · 2026Trial
- Ultrasound-Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach for Postoperative Analgesia Management in Living Liver Donors: A Randomized, Prospective, Controlled Study.Clinical transplantation · 2025Trial
- Adaptation of living donors after liver transplantation in South Korea: an integrative review.Journal of Korean biological nursing science · 2026Article
- A systematic review of the factors significantly influencing the quality of life of living liver donors.International journal of nursing sciences · 2023Review
- Long-term risk of a fatty liver in liver donors.Annals of gastroenterological surgery · 2023Article
- Practice patterns and considerations in liver transplantation from living donors with high BMI: A review.Hepatology forum · 2023Review
- Does living liver donors' underestimation about surgical outcomes impact on their health-related quality of life after donation?: a descriptive cross-sectional study.Health and quality of life outcomes · 2022Article
- Evaluation of Psychosocial Outcomes of Living Liver Donors in Liver Transplantation.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Donor quality of life after living donor liver transplantation: a review of the literature.Digestive medicine research · 2021Article
- Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China.Frontiers in medicine · 2021Article
- [Living related liver transplantation].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- Long-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation.The Journal of surgical research · 2020Article
- Clinical Features and Long-Term Outcomes of Living Donors of Liver Transplantation Who Developed Psychiatric Disorders.Annals of transplantation · 2020Article
- Fatigue, Pain, and Other Physical Symptoms of Living Liver Donors in the Adult-to-Adult Living Donor Liver Transplantation Cohort Study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2018Observational
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundProspective and longitudinal studies have examined liver donors' medical outcomes beyond the first 1 to 2 years postdonation. There is no analogous longitudinal evidence on long-term psychosocial outcomes, including patient-reported clinically significant mental health problems and perceptions of physical well-being. We examined prevalence, descriptive characteristics, and predictors of diagnosable mental health conditions and self-reported physical health problems, including fatigue and pain, in the long-term years after liver donation.
methodsDonors from 9 centers who initially completed telephone interviews at 3 to 10 years postdonation (mean, 5.8 years; SD, 1.9) were reinterviewed annually for 2 years using validated measures. Outcomes were examined descriptively. Repeated-measures regression analyses evaluated potential predictors and correlates of outcomes.
resultsOf 517 donors initially interviewed (66% of those eligible), 424 (82%) were reassessed at least once. Prevalence rates of major depression and clinically significant pain were similar to general population norms; average fatigue levels were better than norms. All prevalence rates showed little temporal change. Anxiety and alcohol use disorder rates exceeded normative rates at 1 or more assessments. Longer postdonation hospitalization, female sex, higher body mass index, concerns about donation-related health effects, and burdensome donation-related financial costs were associated with increased risk for most outcomes (P's < 0.05). Men were at higher risk for alcohol use disorder (P < 0.001).
conclusionsAnxiety and alcohol use disorders were more common than would be expected; they may warrant increased research attention and clinical surveillance. Surveillance for long-term problems in the areas assessed may be optimized by targeting donors at higher risk based on identified predictors and correlates.
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