Evidence map›Paper›PMID 28885270›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2017

Association Between Internalized HIV-Related Stigma and HIV Care Visit Adherence.

Whitney S Rice, Kaylee B Crockett, Michael J Mugavero, James L Raper, Ghislaine C Atkins, Bulent Turan

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Psychometric Properties of the Berger HIV Stigma Scale: A Systematic Review.International journal of environmental research and public health · 2021
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Whitney S Rice*Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL; †Division of Infectious Diseases, School of Medicine, University of Alabama at Birmingham, Birmingham, AL; and ‡School of Nursing, University of Alabama at Birmingham, Birmingham, AL.
Kaylee B Crockett
Michael J Mugavero
James L Raper
Ghislaine C Atkins
Bulent Turan

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
UAB Health Services Research (HSR) Training ProgramT32HS013852 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEVITAN, EMILY B, MUGAVERO, MICHAEL J · 2003 to 2024
$8.0M
Mechanisms and longitudinal effects of stigma on women's adherence and outcomesR01MH104114 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TURAN, JANET M. · 2015 to 2019
$2.9M
AHRQ HHS T32 HS013852NIAID NIH HHS P30 AI027767NIMH NIH HHS R01 MH104114
6 · The paper itself

Abstract

backgroundInternalized HIV-related stigma acts as a barrier to antiretroviral therapy (ART) adherence, but its effects on other HIV care continuum outcomes are unclear.

methodsAmong 196 HIV clinic patients in Birmingham, AL, we assessed internalized HIV-related stigma and depressive symptom severity using validated multi-item scales and assessed ART adherence using a validated single-item measure. HIV visit adherence (attended out of total scheduled visits) was calculated using data from clinic records. Using covariate-adjusted regression analysis, we investigated the association between internalized stigma and visit adherence. Using path analytic methods with bootstrapping, we tested the mediating role of depressive symptoms in the association between internalized stigma and visit adherence and the mediating role of visit adherence in the association between internalized stigma and ART adherence.

resultsHigher internalized stigma was associated with lower visit adherence (B = -0.04, P = 0.04). Black (versus white) race and depressive symptoms were other significant predictors within this model. Mediation analysis yielded no indirect effect through depression in the association between internalized stigma and visit adherence (B = -0.18, SE = 0.11, 95% confidence interval: -0.44 to -0.02) in the whole sample. Supplemental mediated moderation analyses revealed gender-specific effects. Additionally, the effect of internalized stigma on suboptimal ART adherence was mediated by lower visit adherence (B = -0.18, SE = 0.11, 95% confidence interval: -0.44 to -0.02).

conclusionsResults highlight the importance of internalized HIV stigma to multiple and sequential HIV care continuum outcomes. Also, findings suggest multiple intervention targets, including addressing internalized stigma directly, reducing depressive symptoms, and promoting consistent engagement in care.

Indexed as

Patient ComplianceSocial StigmaAdultAgedAnti-HIV AgentsDepressionFemaleHIV InfectionsHumansMaleMiddle AgedYoung AdultAnti-HIV Agents

Identifiers

PMID28885270
PMCPMC5680126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.