Evidence map›Paper›PMID 28884861›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2018

Use of iDXA spine scans to evaluate total and visceral abdominal fat.

J W Bea, C-H Hsu, R M Blew, A P Irving, B J Caan, M L Kwan, I Abraham, S B Going

Open access · greenAbstract readValidation Study
In one paragraph

Article in American journal of human biology : the official journal of the Human Biology Council, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

J W BeaUniversity of Arizona Cancer Center, Tucson, Arizona 85724-5024.
C-H HsuDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724.
R M BlewDepartment of Nutritional Sciences, University of Arizona, Tucson, Arizona 85721.
A P IrvingUniversity of Arizona Cancer Center, Tucson, Arizona 85724-5024.
B J CaanDivision of Research, Kaiser Permanente Northern California, Oakland, California 94612.
M L KwanDivision of Research, Kaiser Permanente Northern California, Oakland, California 94612.
I AbrahamUniversity of Arizona Cancer Center, Tucson, Arizona 85724-5024.
S B GoingDepartment of Nutritional Sciences, University of Arizona, Tucson, Arizona 85721.
University of Arizona · USKaiser Permanente · USUniversity of Arizona Cancer Center

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Teri L Bankhead · 1985 to 2026
$110.2M
Uranium as an Environmental Risk Factor for Cancer Among the NavajoU54CA143924 · NCI · UNIVERSITY OF ARIZONA · PI Gloria D. Coronado · 2009 to 2026
$26.7M
Obesity and bone development in young girlsR01HD074565 · NICHD · UNIVERSITY OF ARIZONA · PI GOING, SCOTT B · 2013 to 2017
$2.6M
Howard Hughes Medical Institute 52006942NCI NIH HHS P30 CA023074NCI NIH HHS U54 CA143924NICHD NIH HHS R01 HD074565
6 · The paper itself

Abstract

objectivesAbdominal fat may be a better predictor than body mass index (BMI) for risk of metabolically-related diseases, such as diabetes, cardiovascular disease, and some cancers. We sought to validate the percent fat reported on dual energy X-ray absorptiometry (DXA) regional spine scans (spine fat fraction, SFF) against abdominal fat obtained from total body scans using the iDXA machine (General Electric, Madison, WI), as previously done on the Prodigy model.

methodsTotal body scans and regional spine scans were completed on the same day (N = 50). In alignment with the Prodigy-based study, the following regions of interest (ROI) were assessed from total body scans and compared to the SFF from regional spine scans: total abdominal fat at (1) lumbar vertebrae L2-L4 and (2) L2-Iliac Crest (L2-IC); (3) total trunk fat; and (4) visceral fat in the android region. Separate linear regression models were used to predict each total body scan ROI from SFF; models were validated by bootstrapping.

resultsThe sample was 84% female, a mean age of 38.5 ± 17.4 years, and mean BMI of 23.0 ± 3.8 kg/m

conclusionsThis replication of the strong correlation between SFF and abdominal fat measures on the iDXA in a new population confirms the previous Prodigy model findings and improves generalizability.

Indexed as

Abdominal FatAbsorptiometry, PhotonAdultArizonaFemaleHumansIntra-Abdominal FatMaleMiddle AgedReproducibility of ResultsSpineWhole Body ImagingYoung Adult

Identifiers

PMID28884861
PMCPMC5785430
OpenAlexW2752302016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.