Evidence map›Paper›PMID 28884402›Full record

ArticleDigestive diseases and sciences2017

Obstructive Sleep Apnea Increases the Risk of Cardiopulmonary Adverse Events Associated with Ambulatory Colonoscopy Independent of Body Mass Index.

Vaishali A Patel, Paul St Romain, Juan Sanchez, Deborah A Fisher, Ryan D Schulteis

Open access · greenAbstract read
In one paragraph

Article in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vaishali A PatelDivision of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, USA. vaishali.patel@emory.edu.
Paul St RomainDivision of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Juan SanchezDepartment of Internal Medicine, Duke University Medical Center, Durham, NC, USA.
Deborah A FisherDivision of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Ryan D SchulteisDepartment of Internal Medicine, Durham Veterans Affairs Medical Center, 508 Fulton Street, Durham, NC, 27705, USA. ryan.schulteis@va.gov.
Duke Medical Center · USDurham VA Medical Center · US

Funding

DUKE TRAINING GRANT IN DIGESTIVE DISEASES AND NUTRITIONT32DK007568 · NIDDK · DUKE UNIVERSITY · PI Katherine Garman, Rodger A. Liddle · 1988 to 2026
$5.6M
NIDDK NIH HHS T32 DK007568
6 · The paper itself

Abstract

backgroundThe relationship between body mass index (BMI) and cardiopulmonary adverse events (CAEs) for ambulatory colonoscopy is unclear.

aimTo assess the association of BMI and CAEs associated with ambulatory colonoscopy.

methodsThis is a retrospective cohort analysis of 418 patients who underwent outpatient colonoscopy at the Durham Veterans Affairs Medical Center categorized as normal/overweight (BMI < 30), obese (BMI 30-34), or morbidly obese (BMI ≥ 35). Adjusted logistic regression analyses were performed.

resultsAt least one CAE occurred in 46.4% of patients (220 events, 72.7% were hypoxia). The rate of CAEs (BMI < 30: 43.8%, BMI 30-34: 48.0%, BMI ≥ 35: 50.6%, p = 0.53) and rate of hypoxia (BMI < 30: 34.8%, BMI 30-34: 40.9%, BMI ≥ 35: 43.2%, p = 0.32) were numerically higher for obese and morbidly obese patients, but not statistically significant. Obese (OR 1.10, 95% CI 0.70-1.73) and morbidly obese (OR 1.07, 95% CI 0.61-1.85) patients did not have an increased risk of CAEs after adjusting for age, ASA class, obstructive sleep apnea (OSA), and type of sedation. OSA was independently associated with an increased risk of CAEs (OR 1.71, 95% CI 1.09-2.74, p = 0.02) after adjusting for BMI, age, ASA class, and type of sedation.

conclusionOSA confers a higher risk of CAEs independent of BMI and sedation type. Consideration of undiagnosed OSA is recommended for appropriate pre-procedure risk stratification. While not statistically significant in this study, there may be clinically significant increased risks of CAEs and hypoxia for patient with BMI > 30 that require further evaluation with larger studies.

Indexed as

Ambulatory CareBody Mass IndexAgedChi-Square DistributionColonoscopyFemaleHeart DiseasesHumansLogistic ModelsLung DiseasesMaleMiddle AgedObesityOdds RatioRetrospective StudiesRisk AssessmentAdverse eventsBody mass indexColonoscopyPatient safety

Identifiers

PMID28884402
PMCPMC5866848
OpenAlexW2751257734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.