Evidence map›Paper›PMID 28884368›Full record

ArticleCardiovascular engineering and technology2017

Anatomical and Optical Properties of Atrial Tissue: Search for a Suitable Animal Model.

Narine Muselimyan, Mohammed Al Jishi, Huda Asfour, Luther Swift, Narine A Sarvazyan

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Narine MuselimyanDepartment of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, 2300 Eye Street NW, Washington, DC, 20052, USA.
Mohammed Al JishiDepartment of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, 2300 Eye Street NW, Washington, DC, 20052, USA.
Huda AsfourDepartment of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, 2300 Eye Street NW, Washington, DC, 20052, USA.
Luther SwiftDepartment of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, 2300 Eye Street NW, Washington, DC, 20052, USA.
Narine A SarvazyanDepartment of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, 2300 Eye Street NW, Washington, DC, 20052, USA. phynas@gwu.edu.ORCID http://orcid.org/0000-0002-2002-5630
George Washington University · US

Funding

New generation of catheters for treatment of atrial fibrillationR42HL120511 · NHLBI · NOCTURNAL PRODUCT DEVELOPMENT, LLC · PI SARVAZYAN, NARINE · 2016 to 2017
$2.3M
New generation of catheters for treatment of atrial fibrillationR41HL120511 · NHLBI · NOCTURNAL PRODUCT DEVELOPMENT, LLC · PI SARVAZYAN, NARINE · 2014 to 2014
$200k
NHLBI NIH HHS R41 HL120511NHLBI NIH HHS R42 HL120511
6 · The paper itself

Abstract

The purpose of this study was to evaluate structural and optical properties of atrial tissue from common animal models and to compare it with human atria. We aimed to do this in a format that will be useful for development of better ablation tools and/or new means for visualizing atrial lesions. Human atrial tissue from clinically relevant age group was compared and contrasted with atrial tissue of large animal models commonly available for research purposes. These included pigs, sheep, dogs and cows. The presented data include area measurements of smooth atrial surface available for ablation and estimates of thickness of collagen and muscle for five different species. We also described methods to quantify presence of collagen and overall thickness of atrial wall. Provided information enables placement of atrial lesions to locations with clinically relevant atrial wall thickness and macroscopic structure ultimately helping investigators to develop better ablation and imaging tools. It also highlights the impact of collagen thickness on optical measurements and lesion visualization.

Indexed as

Ablation TechniquesAgedAge FactorsAnimalsCattleCollagenDogsFemaleHeart AtriaHumansMaleMiddle AgedOrgan Culture TechniquesSheepSpecies SpecificitySwineCollagenAblation lesionsAtrial fibrillationAtrial tissueCatheter developmentCollagenSpectroscopy

Identifiers

PMID28884368
PMCPMC5737901
OpenAlexW2755505478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.