ReviewMolecular biotechnology2017
A Concise Review of MicroRNA Exploring the Insights of MicroRNA Regulations in Bacterial, Viral and Metabolic Diseases.
Review in Molecular biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Regulatory Roles of MicroRNAs in the Pathogenesis of Metabolic Syndrome.Molecular biotechnology · 2024Review
- The role of miRNAs as biomarkers in breast cancer.Frontiers in oncology · 2024Review
- Article
- Wenshen Yiqi Keli Mitigates the Proliferation and Migration of Cigarette Smoke Extract-Induced Human Airway Smooth Muscle Cells through miR-155/FoxO3a Axis.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- miR-142-5p regulates lipopolysaccharide-induced bovine epithelial cell proliferation and apoptosis via targeting BAG5.Experimental and therapeutic medicine · 2021Article
- Is microRNA 1910-3p (miR-1910-3p) a really distinctive marker for psoriasis?Turkish journal of medical sciences · 2021Article
- microRNA-21: a key modulator in oncogenic viral infections.RNA biology · 2021Review
- Human microRNAs in host-parasite interaction: a review.3 Biotech · 2020Review
- The circulating level of miR-122 is a potential risk factor for endothelial dysfunction in young patients with essential hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- MicroRNA‑15a‑5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP‑2 signaling pathway.International journal of molecular medicine · 2020Article
- Article
- Up-regulation of microRNA-203 in influenza A virus infection inhibits viral replication by targeting DR1.Scientific reports · 2018Article
- Association of circulating microRNA-122 with presence and severity of atherosclerotic lesions.PeerJ · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNA (miRNA) is a small section of ribonucleic acid (RNA) that reduces the protein formation by making the pair of the complementary piece of mRNA. The genes of miRNA are present as transcriptional or polycistronic units in the chromosomes. The cellular multiplication, separation and existence like the multitude of genetic functions are affected by miRNA. Nearly 50% of identified miRNA are located in the residence in the intronic part of the genes. The mature miRNA is yielded in two steps. Drosha and RNA-induced silencing complex are the catalysts that play an important role in miRNA synthesis. The miRNA may function by just hindering the translation or complete vitiation of miRNA that occurs to control the genes. The microRNA antagonists and miRNA mimics are therapeutics approaches for the treatment of abnormalities. The upregulation and downregulation of miRNAs are linked to a number of diseases as miR-122 is associated with viral hepatitis, and some members of let-7 and other miRNAs are concerned with various diseases. Overexpressed miRNAs may function as both oncogenes and regulator of cellular processes. The miRNA functions can be altered by single-point mutations in miRNA target and epigenetic silencing of transcription units. There are numerous molecular targets for miRNA as degradation by nuclease and phosphodiesterase. Thus, miRNA has potential applications in disease diagnosis along with therapy, but the mechanisms involved in miRNA systems and its targeted delivery of miRNA are much more important to achieve its therapeutic applications.
Indexed as
Identifiers
28884294What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.