Evidence map›Paper›PMID 28884229›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017

Time-to-event analysis of surgically treated posthemorrhagic hydrocephalus in preterm infants: a single-institution retrospective study.

Rowland H Han, Daniel Berger, Mohamed Gabir, Brandon S Baksh, Diego M Morales, Amit M Mathur, Christopher D Smyser, Jennifer M Strahle, David D Limbrick

Abstract read
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rowland H HanDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA. rowland.han@wustl.edu.
Daniel BergerDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
Mohamed GabirDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
Brandon S BakshDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
Diego M MoralesDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
Amit M MathurDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Christopher D SmyserDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Jennifer M StrahleDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
David D LimbrickDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis Children's Hospital, One Children's Place, Suite 4S20, St. Louis, MO, 63110, USA.
Neurological Surgery · USSt. Louis Children's Hospital · USWashington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
PREDICTING CHILDHOOD OUTCOMES IN PRETERM INFANTS USING CEREBRAL CONNECTIVITYK02NS089852 · NINDS · WASHINGTON UNIVERSITY · PI SMYSER, CHRISTOPHER DANIEL · 2014 to 2018
$848k
NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCRR NIH HHS UL1 RR024992NICHD NIH HHS U54 HD087011NINDS NIH HHS K02 NS089852
6 · The paper itself

Abstract

purposeThe purpose of this study is to report time points relevant to the neurosurgical management of posthemorrhagic hydrocephalus (PHH).

methodsData were collected retrospectively on 104 preterm infants with intraventricular hemorrhage (IVH) who received neurosurgical intervention for PHH at St. Louis Children's Hospital from 1994 to 2016. Kaplan-Meier curves were constructed for various endpoints.

resultsIVH grade on head ultrasound obtained through routine clinical care was II, III, and IV in 5 (4.8%), 33 (31.7%), and 66 (63.5%) of the patients, respectively. Neither IVH size nor location appeared to affect development of PHH. Days from birth to IVH, ventriculomegaly, temporizing neurosurgical procedure (TNP), and permanent neurosurgical intervention were 2.0 (95% CI 1.7-2.3), 3.0 (2.5-3.5), 24.0 (22.2-25.8), and 101.0 (90.4-111.6), respectively. Grades III and IV IVH did not differ in age at IVH diagnosis (Χ

conclusionsAlthough most infants who develop IVH and ventriculomegaly will do so within a few days of birth, at-risk infants should be observed for at least 4 weeks with serial head ultrasounds to monitor for PHH requiring surgery.

Indexed as

Cerebral HemorrhageFemaleHumansHydrocephalusInfant, NewbornInfant, PrematureKaplan-Meier EstimateMaleProportional Hazards ModelsRetrospective StudiesRisk FactorsIntraventricular hemorrhageTemporizing neurosurgical procedureVentriculomegalyVentriculoperitoneal shunt

Identifiers

PMID28884229
PMCPMC5647248
OpenAlexW2751400953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.