ArticleInternational journal of colorectal disease2017
Safety of endoscopic mucosal resection (EMR) of large non-pedunculated colorectal adenomas in the elderly.
Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Cold EMR vs. Hot EMR for the removal of sessile serrated polyps larger than 10 mm: a systematic review and meta-analysis.BMC surgery · 2024Pooled it
- Efficacy of cyanoacrylate in the prevention of delayed bleeding after endoscopic mucosal resection of large colorectal polyps: a pilot study.International journal of colorectal disease · 2020Trial
- Underwater versus conventional endoscopic mucosal resection for small size non-pedunculated colorectal polyps: a randomized controlled trial : (UEMR vs. CEMR for small size non-pedunculated colorectal polyps).BMC gastroenterology · 2020Trial
- Observational
- High-risk adenoma predicts delayed post-polypectomy bleeding: a size-stratified retrospective cohort study and risk score development.Frontiers in medicine · 2026Article
- Outcomes of Underwater Endoscopic Mucosal Resection for Giant Colorectal Polyps: A Multicenter Study.Endoscopy international open · 2026Article
- S-EMR: A first experience with stalked endoscopic mucosal resection in thick and high-risk pedunculated polyps.Surgery open science · 2025Article
- Review
- Article
- Endoscopic management of difficult laterally spreading tumors in colorectum.World journal of gastrointestinal endoscopy · 2022Review
- Risk Stratification of Endoscopic Submucosal Dissection in Colon Tumors.Journal of clinical medicine · 2022Article
- Endoscopic Management of Complex Colorectal Polyps: Current Insights and Future Trends.Frontiers in medicine · 2021Review
- Outcomes and adverse factors for endoscopic mucosal resection (EMR) of colorectal polyps in elderly patients.Frontline gastroenterology · 2021Article
- Colon mucosal neoplasia referred for endoscopic mucosal resection: Recurrence of adenomas and prediction of submucosal invasion.World journal of gastrointestinal endoscopy · 2020Article
- Endoscopic mucosal resection with anchoring of the snare tip: multicenter retrospective evaluation of effectiveness and safety.Endoscopy international open · 2019Article
- Safety of endoscopic mucosal resection of large colonic polyps in elderly patients: a systematic review and meta-analysis.Annals of gastroenterologyArticle
- Current endoscopic closure techniques for the management of gastrointestinal perforations.Therapeutic advances in gastrointestinal endoscopyReview
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic mucosal resection (EMR) has been proven to be safe and effective for the treatment of colorectal adenomas. However, data are limited on the safety of this technique for large polyps and in elderly patients. Aims of our study were to examine the bleeding and perforation rates in patients with large non-pedunculated adenomas (≥20mm) and to evaluate the influence of size (≥40mm) and age (≥75 years) on the complication rates.
methodsIn this multicenter retrospective study, patients who underwent EMR of non-pedunculated adenomas ≥20mm between January 2012 and March 2016 were included. The demographics of the patients, the use of antithrombotic drugs, size of the polyps, type of resection, pathology report, occurrence of post-polypectomy bleeding, and perforation- and recurrence rate were collected.
resultsIn 343 patients, 412 adenomas were removed. Eighty patients (23.3%) were ≥75 years of age, 138 polyps (33.5%) were ≥40mm. Bleeding complications were observed in 28 cases (6.8%) and were found significantly more frequent in adenomas ≥40mm, independent of the use of antithrombotic therapy. Five perforations (1.2%) were described, not related to the size of the polyp. There was no significant difference in complication rates between patients <75 years and patients ≥75 years. Bleeding complications rates were significantly higher in patients receiving double antithrombotic therapy.
conclusionEMR is safe in elderly patients. EMR of adenomas of ≥40mm was associated with more bleeding complications. Future studies should address how the bleeding rates can be reduced in these patients, especially in those who use double antithrombotic treatment.
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