ArticleRevista brasileira de ortopedia
Diffuse pigmented villonodular synovitis in knee joint: diagnosis and treatment.
Article in Revista brasileira de ortopedia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Arthroscopic Versus Open Management of Diffuse-Type Tenosynovial Giant Cell Tumor of the Knee: A Meta-analysis of Retrospective Cohort Studies.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021Pooled it
- Benign intra-articular soft tissue tumors mimicking hip septic arthritis: an arthroscopic case series with tenosynovial giant cell tumor predominance.BMC musculoskeletal disorders · 2026Article
- Optimal clinical management of tenosynovial giant cell tumours: a UK perspective.Bone & joint open · 2026Article
- Recurrence of arthroscopic treatment of pigmented villonodular synovitis of the knee: A systematic review and meta-analysis.Journal of experimental orthopaedics · 2025Review
- Localized Pigmented Villonodular Synovitis in the Shoulder: Report of a Case Treated through Arthroscopy.Revista brasileira de ortopedia · 2024Article
- Article
- T2-star (T2*)-weighted magnetic resonance imaging of tenosynovial giant cell tumors.European journal of radiology open · 2023Article
- Total Synovectomy and Bone Grafting/Cementation after Curettage of the Bone Lesion in Diffuse Type of Tenosynovial Giant Cell Tumor: A Retrospective Cohort Study.The archives of bone and joint surgery · 2023Article
- Combined type of nodular and diffuse forms of pigmented villonodular synovitis in a single knee joint of a child.Clinical case reports · 2022Article
- Malignant giant cell tumors of the tendon sheath of the right hip: A case report.World journal of clinical cases · 2022Article
- Tenosynovial Giant Cell Tumor Mimicking Acute Septic Arthritis of the Hip: A Case Report.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Tenosynovial giant cell tumor-diffuse type, treated with a novel colony-stimulating factor inhibitor, pexidartinib: initial experience with MRI findings in three patients.Skeletal radiology · 2022Article
- Case report: left atrial Myxoma causing elevated C-reactive protein, fatigue and fever, with literature review.BMC cardiovascular disorders · 2020Review
- Multiple systemic treatment options in a patient with malignant tenosynovial giant cell tumour.Anti-cancer drugs · 2020Article
- Pigmented villonodular synovitis of the temporomandibular joint: case report and the literature review for postoperative radiotherapy.Journal of radiology case reports · 2019Review
- Osteochondral Lesion in Diffuse Pigmented Villonodular Synovitis of the Knee.Knee surgery & related research · 2019Article
- Localized Pigmented Villonodular Synovitis of the Posterior Knee Compartment with Popliteal Vessel Compression: A Case Report of Arthroscopic Resection Using Only Anterior Knee Portals.Case reports in orthopedics · 2018Article
- Clinical outcomes of diffuse PVNS of the knee following arthroscopic complete synovectomy±posterior open resection.Journal of orthopaedicsArticle
- Localized Pigmented Villonodular Synovitis of the Knee Co-existing with Extra-articular Nodular Synovitis of the Popliteus Tendon Sheath: A Case Report.Journal of the West African College of SurgeonsArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pigmented villonodular synovitis is a rare proliferative condition of the synovium. Although the condition can present in any joint, the knee is the most commonly affected site. Despite being a benign condition, pigmented villonodular synovitis is often aggressive, with marked extra-articular extension in some cases. Monoarticular involvement occurs in two forms: localized and diffuse. The latter is more common, with a high recurrence rate. There is no standard method of management of this lesion. Open surgery is a classical and effective method for treatment. Arthroscopic synovectomy, however, has gained popularity, and has several advantages over the open technique particularly in exclusively articular cases. The combined approach is suggested in cases with extra-articular involvement. Synovectomy through any approach may prevent secondary osteoarthritis and subsequent joint arthroplasty. Internal irradiation or external beam radiation as an adjuvant treatment to surgical synovectomy appears to decrease the rate of local recurrence in diffuse cases. The authors observed a great heterogeneity in reporting of functional results, and specific conclusions should not be drawn. Each patient should be managed in accordance with his/her particular condition.
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Registered trials
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