Evidence map›Paper›PMID 28884073›Full record

ReviewNeuroImage. Clinical2017

Connectome-based lesion-symptom mapping (CLSM): A novel approach to map neurological function.

Ezequiel Gleichgerrcht, Julius Fridriksson, Chris Rorden, Leonardo Bonilha

Abstract readReview
In one paragraph

Review in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Language Recovery after Brain Injury: A Structural Network Control Theory Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Trial
  2. The Influence of Contralesional Brain Age Gradients on Chronic Stroke Aphasia Severity and Treatment Response.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Critical-Network Lesion-Symptom Mapping.Human brain mapping · 2026
    Article
  4. Observational
  5. Gene Expression-Based Lesion-Symptom Mapping:The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  6. Article
  7. Current Clinical Applications of Structural MRI in Neurological Disorders.Journal of clinical neurology (Seoul, Korea) · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Lesion mapping in neuropsychological research: A practical and conceptual guide.Cortex; a journal devoted to the study of the nervous system and behavior · 2024
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezequiel GleichgerrchtDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.
Julius FridrikssonDepartment of Communication Sciences and Disorders, University of South Carolina, Columbia, SC, USA.
Chris RordenDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
Leonardo BonilhaDepartment of Neurology, Medical University of South Carolina, Charleston, SC, USA.

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
Cortical and Subcortical Organization of Language-Related Semantic Processing in Alzheimer's DiseaseR01DC014021 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BONILHA, LEONARDO F · 2014 to 2023
$4.7M
NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC014021
6 · The paper itself

Abstract

Lesion-symptom mapping is a key tool in understanding the relationship between structure and function in neuroscience as it can provide objective evidence about which regions are

Indexed as

ConnectomeHumansConnectome-based lesion-symptom mappingConnectomicsDiffusion tensor imagingVoxel-based lesion-symptom mapping

Identifiers

PMID28884073
PMCPMC5581860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.