Evidence map›Paper›PMID 28883989›Full record

ArticleFuture science OA2017

Osteoinductive effects of preoperative dexamethasone in human dental pulp stem cells primary culture.

Rani da Cunha Moretti, Monica Talarico Duailibi, Paulo Oliveira Martins, Jennifer Adriane Dos Santos, Silvio Eduardo Duailibi

Open access · goldAbstract read
In one paragraph

Article in Future science OA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rani da Cunha MorettiCTCMol, Center of Cellular & Molecular Therapy, UNIFESP- Universidade Federal, de São Paulo- Escola Paulista de Medicina, São Paulo, Brazil.
Monica Talarico DuailibiCTCMol, Center of Cellular & Molecular Therapy, UNIFESP- Universidade Federal, de São Paulo- Escola Paulista de Medicina, São Paulo, Brazil.
Paulo Oliveira MartinsOral & Maxillofacial Surgery Department, Hospital Ipiranga, São Paulo, Brazil.
Jennifer Adriane Dos SantosCTCMol, Center of Cellular & Molecular Therapy, UNIFESP- Universidade Federal, de São Paulo- Escola Paulista de Medicina, São Paulo, Brazil.
Silvio Eduardo DuailibiCTCMol, Center of Cellular & Molecular Therapy, UNIFESP- Universidade Federal, de São Paulo- Escola Paulista de Medicina, São Paulo, Brazil.
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe use of dexamethasone (DEX) in mesenchymal cell culture induces osteoblastic differentiation and, consequently, formation of mineralized tissues. Tissue engineering proposes the development of therapeutic strategies aimed at structural and functional regeneration of biological tissues. In this sense, cell characterization METHODOLOGY: Cells from the third molar pulp were divided into two experimental groups, each with two preoperative medication protocols used in dental practice and differentiated by the intake of DEX in one of them. The assessment of proliferation, differentiation and viability through trypan blue, methylthiazol tetrazolium, and von Kossa and alizarin red assays, respectively, were held within fixed intervals: 7, 14, 21 and 28 days.

conclusionThis study has shown that DEX may influence

Indexed as

dexamethasonehDPSChuman dental pulp stem cellsthird molartissue engineering

Identifiers

PMID28883989
PMCPMC5583691
OpenAlexW2604646237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.