ArticleJournal of animal science and biotechnology2017
Betaine affects muscle lipid metabolism via regulating the fatty acid uptake and oxidation in finishing pig.
Article in Journal of animal science and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Effect of Betaine on Reducing Body Fat-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Nutrients · 2019Pooled it
- The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial.Journal of the International Society of Sports Nutrition · 2018Trial
- Effects of Dietary Betaine on Growth Performance, Serum Metabolites, and Meat Quality of Pigs: A Meta-Analysis.Animals : an open access journal from MDPI · 2026Review
- Multi-Omics Integration Reveals Key Genes, Metabolites and Pathways Underlying Meat Quality and Intramuscular Fat Deposition Differences Between Tibetan Pigs and Duroc × Tibetan Crossbred Pigs.Animals : an open access journal from MDPI · 2026Article
- Arecoline regulates glycolipid and endoplasmic reticulum metabolisms in adult grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model.Nutrients · 2025Article
- Effects of defined voluntary running distances coupled with high-fat diet consumption on the skeletal muscle transcriptome of male mice.Physiological reports · 2025Article
- Betaine supplementation affects carbohydrate metabolism in the skeletal muscle of finishing pigs.PloS one · 2025Article
- Transcriptomics and metabolomics insights into the seasonal dynamics of meat quality in yak on the Qinghai-Tibetan Plateau.BMC genomics · 2024Article
- Betaine and L-Carnitine Synergistically Influence the Metabolome and Immune Response in Dogs.Animals : an open access journal from MDPI · 2024Article
- Lipo-nutritional quality of pork: The lipid composition, regulation, and molecular mechanisms of fatty acid deposition.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats.Chinese medicine · 2023Article
- Article
- Long-Term Dietary Supplementation with Betaine Improves Growth Performance, Meat Quality and Intramuscular Fat Deposition in Growing-Finishing Pigs.Foods (Basel, Switzerland) · 2023Article
- The effects of dietary essential fatty acid ratios and linoleic acid level in grow-finish pigs.Journal of animal science · 2023Article
- Effects of low-energy diet supplemented with betaine on growth performance, nutrient digestibility, and serum metabolomic profiles in growing pigs.Journal of animal science · 2023Article
- CHDH, a key mitochondrial enzyme, plays a diagnostic role in metabolic disorders diseases and tumor progression.Frontiers in genetics · 2023Review
- Performance, Carcass Traits, Pork Quality and Expression of Genes Related to Intramuscular Fat Metabolism of Two Diverse Genetic Lines of Pigs.Foods (Basel, Switzerland) · 2022Article
- Dietary methionine deficiency stunts growth and increases fat deposition via suppression of fatty acids transportation and hepatic catabolism in Pekin ducks.Journal of animal science and biotechnology · 2022Article
- Dietary Betaine and Fatty Acids Change Circulating Single-Carbon Metabolites and Fatty Acids in the Dog.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBetaine affects fat metabolism in animals, but the specific mechanism is still not clear. The purpose of this study was to investigate possible mechanisms of betaine in altering lipid metabolism in muscle tissue in finishing pigs.
methodsA total of 120 crossbred gilts (Landrace × Yorkshire × Duroc) with an average initial body weight of 70.1 kg were randomly allotted to three dietary treatments. The treatments included a corn-soybean meal basal diet supplemented with 0, 1250 or 2500 mg/kg betaine. The feeding experiment lasted 42 d.
resultsBetaine addition to the diet significantly increased the concentration of free fatty acids (FFA) in muscle (
conclusionsThe results suggested that betaine may promoted muscle fatty acid uptake via up-regulating the genes related to fatty acid transporter including
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.