Evidence map›Paper›PMID 28883861›Full record

ArticleArchives of medical science : AMS2017

Bioavailable testosterone is independently associated with Fatty Liver Index in postmenopausal women.

Aleksandra Klisic, Nebojsa Kavaric, Milovan Jovanovic, Ivan Soldatovic, Najdana Gligorovic-Barhanovic, Jelena Kotur-Stevuljevic

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Fatty liver index (FLI): more than a marker of hepatic steatosis.Journal of physiology and biochemistry · 2024
    Pooled it
  2. Trial
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  6. Adipokines and their role in acute pancreatitis.Journal of medical biochemistry · 2024
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  17. Are total bilirubin and high-sensitivity C-reactive protein independently associated with Type 2 diabetes mellitus in postmenopausal women?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Article
  18. Article
  19. Article
  20. [Research progress of non-alcoholic fatty liver disease in postmenopausal women].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Aleksandra KlisicCenter of Laboratory Diagnostics, Primary Health Care Center, Podgorica, Montenegro.
Nebojsa KavaricCenter of Laboratory Diagnostics, Primary Health Care Center, Podgorica, Montenegro.
Milovan JovanovicCenter of Laboratory Diagnostics, Primary Health Care Center, Podgorica, Montenegro.
Ivan SoldatovicInstitute for Biostatistics, Medical Informatics and Researches in Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Najdana Gligorovic-BarhanovicCenter of Clinical Laboratory Diagnostics, Clinical Center of Montenegro, Podgorica, Montenegro.
Jelena Kotur-StevuljevicDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
University of Montenegro · MEUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious studies have examined the correlation between hyperandrogenemia and non-alcoholic fatty liver disease (NAFLD) in women and showed contradictory results. Therefore, we aimed to evaluate the relationship between testosterone level and Fatty Liver Index (FLI), as a surrogate marker for NAFLD, in a cohort of postmenopausal women. MATERIAL AND

methodsA total of 150 postmenopausal women were included in this cross-sectional study. Anthropometric and biochemical parameters, as well as blood pressure, were obtained. Non-alcoholic fatty liver disease is assessed by FLI, an algorithm based on body mass index, waist circumference, triglycerides and γ-glutamyl transferase, as a simple and accurate predictor of hepatic steatosis. Women were divided into three groups (FLI < 30,

resultsMultiple linear regression analysis revealed that the best model consisted of 4 parameters (e.g., bioavailable testosterone (β = 0.288,

conclusionsBioavailable testosterone is independently associated with FLI in postmenopausal women.

Indexed as

fatty liverhyperandrogenemiainsulin resistanceobesitypostmenopausal

Identifiers

PMID28883861
PMCPMC5575228
OpenAlexW2742541060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.