ReviewFrontiers in physiology2017
A Meta-Analysis on Sex Differences in Resting-State Vagal Activity in Children and Adolescents.
Review in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07244198 (CFT@TeenSAD - Understanding the Impact of Online Delivered Compassion Focused Therapy on Social Anxiety Symptoms, Emotion Regulation and Heart Rate Variability.), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CFT@TeenSAD - Understanding the Impact of Online Delivered Compassion Focused Therapy on Social Anxiety Symptoms, Emotion Regulation and Heart Rate Variability.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autonomic nervous system correlates of posttraumatic stress symptoms in youth: Meta-analysis and qualitative review.Clinical psychology review · 2022Pooled it
- Hair cortisol concentration and basal heart rate variability differentiate long COVID from depressive disorders in youth.Comprehensive psychoneuroendocrinology · 2026Article
- Stress reactivity of the autonomic nervous system in youth with and without major depressive disorder.European child & adolescent psychiatry · 2026Article
- Article
- Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Review
- Capturing sex differences in spontaneous autonomic fluctuations of resting heart rate using a similarity graph theory approach.Biology of sex differences · 2026Article
- Article
- Variation in coupling across neural and cardiac systems of regulation is linked to markers of anxiety risk in preschool.Development and psychopathology · 2025Article
- Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study.Journal of neurodevelopmental disorders · 2025Article
- The role of the sympathetic component of the autonomic nervous system on pain before and after third molar extraction- an observational cohort study.BMC anesthesiology · 2025Observational
- Heart rate variability and cognitive functions in adolescents with complex congenital heart disease.Pediatric research · 2025Article
- Associations between the quality of family interactions during a mother-father-adolescent conflict discussion task and physiological emotion regulation in adolescents.PLOS mental health · 2025Article
- Early life microbiome disbalance impacts neuroendocrine outcomes in pre-pubertal mice in a sexually dimorphic manner.Frontiers in microbiology · 2025Article
- Cognitive control processes and emotion regulation in adolescence: Examining the impact of affective inhibition and heart-rate-variability on emotion regulation dynamics in daily life.Developmental cognitive neuroscience · 2024Article
- Resting heart rate associations with violence exposure and posttraumatic stress symptoms: sex differences in children.Biology of sex differences · 2024Article
- A sex-specific pathway linking early life maltreatment, vagal activity, and depressive symptoms.European journal of psychotraumatology · 2024Article
- Cardiac Autonomic Balance Is Altered during the Acute Stress Response in Adolescent Major Depression-Effect of Sex.Life (Basel, Switzerland) · 2023Article
- Development and Parasympathetic Regulation in Male and Female Adolescents with Autism Spectrum Disorder: A Two-Timepoint Longitudinal Study.Journal of autism and developmental disorders · 2023Article
- Resting respiratory sinus arrhythmia is related to emotion reactivity to social-evaluative stress.Journal of affective disorders · 2023Article
- Sex Moderates the Relationship Between Nausea Severity and Heart Rate Variability in Adolescents and Young Adults.Digestive diseases and sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower vagal activity is associated with psychopathology independent of age. Research suggests that alterations of vagal activity precede the development of psychopathology. The present review aimed to quantify sex differences in vagal activity in children and adolescents. Studies reporting on sex differences on measures of vagally-mediated heart rate variability derived from short-term recordings under resting conditions in boys and girls were included. Drawing on data from more than 5,000 children and adolescents, we provide evidence that healthy young girls display lower vagal activity and greater mean heart rate compared to boys, a finding that may have implications for risk associated with the development of internalizing psychopathology and somatic ill-health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.