Evidence map›Paper›PMID 28883733›Full record

ArticleNeuropsychiatric disease and treatment2017

Fan the flame: trazodone-induced mania in a unipolar depressed patient with stable sertraline treatment.

Jianbo Hu, Jianbo Lai, Hanzhi Zheng, Shaohua Hu, Yi Xu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Neuropsychiatric disease and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jianbo Hu *Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jianbo Lai *Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hanzhi ZhengDepartment of Clinical Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Shaohua HuDepartment of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi XuDepartment of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
First Affiliated Hospital Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depressed patients often complain of sleep disturbance. Routine antidepressive strategies sometimes fail to deal with this intractable issue. Indeed, the supplementation of sleep promoting antidepressants (eg, trazodone, mirtazapine, and agomelatine) is prevalent in clinical practice. However, the combination of different antidepressants may increase the affective lability. Herein, we document a patient with unipolar depression who was compliant with sertraline treatment and who dramatically switched to mania after adding trazodone as a sleeping aid. This case extended our understanding of the potential manic-switching risk when trazodone is used to promote sleep.

Indexed as

depressionmaniasertralinetrazodone

Identifiers

PMID28883733
PMCPMC5576708
OpenAlexW2746486584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.