Evidence map›Paper›PMID 28883719›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2017

Incidence and risk factors of atrial fibrillation in Asian COPD patients.

Kuang-Ming Liao, Chung-Yu Chen

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Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

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24citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Kuang-Ming LiaoDepartment of Internal Medicine, Chi Mei Medical Center Chiali, Tainan.
Chung-Yu ChenMaster Program in Clinical Pharmacy, School of Pharmacy, Kaohsiung Medical University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the incidence and risk factors of atrial fibrillation (AF) in Asian chronic obstructive pulmonary disease (COPD) patients. PATIENTS AND

methodsWe selected a study population older than 40 years with a COPD diagnosis and who had used at least one inhaled bronchodilator medication between 1998 and 2012. The date of the index COPD diagnosis was defined as the index date. We excluded patients with a history of AF, significant mitral valve disease, disorders of the thyroid gland, or ischemic heart disease before the index date. We followed all patients from the index date to the day of AF occurrence, the day of death, or the date of December 31, 2013. The baseline of comorbidities was identified before the index date. Comorbidities included hypertension, diabetes mellitus, end-stage renal disease, congenital heart failure, stroke, peripheral arterial occlusive disease, and malignancy.

resultsWe included 6,208 COPD patients and 12,409 patients without COPD. The incidence of AF was higher in COPD patients than in those without COPD. The adjusted hazard ratio (HR) for AF among those with COPD was 2.23 with a 95% confidence interval (CI) of 1.98-2.51 compared to those without COPD. After multiple analyses, patients with hypertension (HR 1.43 [95% CI =1.26-1.62]) or heart failure (HR 2.36 [95% CI =1.81-3.08]) were found to have a significantly higher incidence of AF than those without these conditions.

conclusionIt is important for physicians to monitor, prevent, and provide early intervention for AF in COPD patients with hypertension or heart failure.

Indexed as

Asian PeopleAdultAgedAtrial FibrillationComorbidityDatabases, FactualFemaleHeart FailureHumansHypertensionIncidenceKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsPulmonary Disease, Chronic Obstructiveatrial fibrillationCOPDincidence

Identifiers

PMID28883719
PMCPMC5574688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.