Evidence map›Paper›PMID 28883708›Full record

ArticleWorld journal of gastroenterology2017

Rarity among benign gastric tumors: Plexiform fibromyxoma - Report of two cases.

Kinga Szurian, Holger Till, Eva Amerstorfer, Nicole Hinteregger, Hans-Jörg Mischinger, Bernadette Liegl-Atzwanger, Iva Brcic

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Giant plexiform fibromyxoma of the esophagus.Wiener klinische Wochenschrift · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Gastric Plexiform Fibromyxoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Article
  11. Article
  12. Gastric aggressive fibromatosis: report of a case and review of the literature.International journal of clinical and experimental pathology · 2019
    Article
  13. An Update on Clinicopathological and Molecular Features of Plexiform Fibromyxoma.Canadian journal of gastroenterology & hepatology · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kinga SzurianInstitute of Pathology, Medical University of Graz, 8036 Graz, Austria.
Holger TillDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8036 Graz, Austria.
Eva AmerstorferDepartment of Paediatric and Adolescent Surgery, Medical University of Graz, 8036 Graz, Austria.
Nicole HintereggerDepartment of Radiology, Division of Neuroradiology, Vascular and Interventional Radiology, Medical University of Graz, 8036 Graz, Austria.
Hans-Jörg MischingerDepartment of Surgery, Medical University of Graz, 8036 Graz, Austria.
Bernadette Liegl-AtzwangerInstitute of Pathology, Medical University of Graz, 8036 Graz, Austria.
Iva BrcicInstitute of Pathology, Medical University of Graz, 8036 Graz, Austria. iva.brcic@medunigraz.at.
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plexiform fibromyxoma is a very rare mesenchymal tumor of the stomach, found almost exclusively in the antrum/pylorus region. The most common presenting symptoms are anemia, hematemesis, nausea and unintentional weight loss, without sex or age predilection. We describe here two cases of plexiform fibromyxoma, involving a 16-year-old female and a 34-year-old male. Both patients underwent complete resection (R0) by distal gastrectomy and retrocolic gastrojejunostomy (according to Billroth 2); for both, the postoperative course was uneventful. Histology showed multiple intramural and subserosal nodules with characteristic plexiform growth, featuring bland spindle cells situated in an abundant myxoid stroma with low mitotic activity. Immunohistochemistry showed α-smooth muscle actin-positive spindle cells, focal positivity for CD10, and negative staining for KIT, DOG1, CD34, S100, β-catenin, STAT-6 and anaplastic lymphoma kinase. One of the cases showed focal positivity for h-caldesmon and desmin. Upon follow-up, no sign of disease was found. In the differential diagnosis of plexiform fibromyxoma, it is important to exclude the more common gastrointestinal stromal tumors as they have greater potential for aggressive behavior. Other lesions, like neuronal and vascular tumors, inflammatory fibroid polyps, abdominal desmoid-type fibromatosis, solitary fibrous tumors and smooth muscle tumors, must also be excluded.

Indexed as

AdolescentAdultAnoctamin-1Biomarkers, TumorCalmodulin-Binding ProteinsDiagnosis, DifferentialFemaleFibromaGastrectomyGastric BypassGastrointestinal Stromal TumorsHumansMagnetic Resonance ImagingMaleNeoplasm ProteinsPositron Emission Tomography Computed TomographyANO1 protein, humanAnoctamin-1Biomarkers, TumorCALD1 protein, humanCalmodulin-Binding ProteinsNeoplasm ProteinsProto-Oncogene Proteins c-kitBenign gastric tumorGastrointestinal stromal tumorPlexiform angiomyxoid myofibroblastic tumorPlexiform fibromyxomaStomach

Identifiers

PMID28883708
PMCPMC5569297
OpenAlexW2745342888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.