ArticleScientific reports2017
The presence of acquired enamel pellicle changes acid-induced erosion from dissolution to a softening process.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Pooled it
- In vivo assessment of the Optipen optical reflectometer for detecting enamel surface changes following an erosive challenge.Clinical oral investigations · 2026Trial
- Short-term effects of sweetened acidic beverages consumption on human saliva: Colloidal properties and protein composition.PloS one · 2025Article
- Salivary Proteins in Human Acquired Enamel Pellicle (AEP) on Eroded and Uneroded Teeth in Patients with Gastro-Oesophageal Reflux Disease (GORD).Dentistry journal · 2024Article
- Salivary Proteins and Metabolites as Caries Biomarkers in Adolescents.Caries research · 2024Article
- Impact of Dentistry Materials on Chemical Remineralisation/Infiltration versus Salivary Remineralisation of Enamel-In Vitro Study.Materials (Basel, Switzerland) · 2022Article
- The interplay of saliva, erosion and attrition on enamel and dentine.The Saudi dental journal · 2022Article
- Effect of fluoride mouthrinses and stannous ions on the erosion protective properties of the in situ pellicle.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erosive wear undermines the structural properties of enamel resulting in irreversible enamel loss. A thin protein layer formed from natural saliva on tooth surfaces, acquired enamel pellicle (AEP), protects against erosive wear. The exact components in saliva responsible for such protection are not yet known. We prepared three solutions containing different components: proteins and ions [natural saliva (NS)], minerals with no proteins [artificial saliva (AS)] and neither proteins nor ions [deionised water (DW)]. To assess the protection of the three solutions against citric acid enamel erosion, enamel specimens were immersed in the corresponding solution for 24 h. All specimens were then exposed to five erosion cycles, each consisted of a further 30 min immersion in the same solution followed by 10-min erosion. Mean step height using a non-contacting profilometer, mean surface microhardness (SMH) using Knoop microhardness tester (final SMH), and roughness and 2D profiles using atomic force microscopy were measured after five cycles. The final SMH values were compared to the starting values (after 24 hr). NS group had significantly less tissue loss but greater SMH change (P < 0.0001) than AS and DW groups. Specimens in NS were softer and rougher (P < 0.001) but less eroded than specimens in AS and DW.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.