ArticleScientific reports2017
A somatotopic bidirectional hand prosthesis with transcutaneous electrical nerve stimulation based sensory feedback.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 221 citations in OpenAlex.
- Artificial referred sensation in upper and lower limb prosthesis users: a systematic review.Journal of neural engineering · 2022Pooled it
- Immersive virtual reality with synchronous neurostimulation for upper-limb recovery after stroke: a randomized feasibility trial.Nature medicine · 2026Trial
- A methodological framework for the efficient characterization of peripheral nerve stimulation parameters.Journal of neural engineering · 2025Trial
- First-in-human implementation of a bidirectional somatosensory neuroprosthetic system with wireless communication.Journal of neuroengineering and rehabilitation · 2025Trial
- Sensory and cortical biomarkers unveil pain modulation mechanisms induced by targeted multisensory neurostimulation.Journal of neuroengineering and rehabilitation · 2026Article
- Enhanced sensory perception and myoelectric control with high channel count implanted sensorimotor systems.Journal of neural engineering · 2025Article
- Ultra-conformable tattoo electrodes for providing sensory feedback via transcutaneous electrical nerve stimulation.Scientific reports · 2025Article
- Optimization frameworks for bespoke sensory encoding in neuroprosthetics.APL bioengineering · 2025Article
- The Next Frontier in Neuroprosthetics: Integration of Biomimetic Somatosensory Feedback.Biomimetics (Basel, Switzerland) · 2025Review
- Assessing the utility of Regenerative Peripheral Nerve Interfaces (RPNIs) in providing referred sensations in a functional task in a virtual environment.IEEE transactions on medical robotics and bionics · 2025Article
- A novel portable device and validation procedure for transcutaneous electrical nerve stimulation.Wearable technologies · 2025Article
- Altered tactile abnormalities in children with ASD during tactile processing and recognition revealed by dynamic EEG features.Frontiers in psychiatry · 2025Article
- Restoring Somatotopic Sensory Feedback in Lower Limb Amputees through Noninvasive Nerve Stimulation.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Wearable non-invasive neuroprosthesis for targeted sensory restoration in neuropathy.Nature communications · 2024Article
- Enhancing neuroprosthesis calibration: the advantage of integrating prior training over exclusive use of new data.Journal of neural engineering · 2024Article
- Sensory integration for neuroprostheses: from functional benefits to neural correlates.Medical & biological engineering & computing · 2024Review
- Agonist-antagonist myoneural interface surgery on the proprioceptive reconstruction of rat hind limb.Heliyon · 2024Article
- A preliminary study exploring the effects of transcutaneous spinal cord stimulation on spinal excitability and phantom limb pain in people with a transtibial amputation.Journal of neural engineering · 2024Article
- Enhancing touch sensibility with sensory electrical stimulation and sensory retraining.Journal of neuroengineering and rehabilitation · 2024Article
- Green Synthesized Chitosan Nanoparticles for Controlling Multidrug-ResistantInternational journal of molecular sciences · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to amputees, sensory feedback is amongst the most important features lacking from commercial prostheses. Although restoration of touch by means of implantable neural interfaces has been achieved, these approaches require surgical interventions, and their long-term usability still needs to be fully investigated. Here, we developed a non-invasive alternative which maintains some of the advantages of invasive approaches, such as a somatotopic sensory restitution scheme. We used transcutaneous electrical nerve stimulation (TENS) to induce referred sensations to the phantom hand of amputees. These sensations were characterized in four amputees over two weeks. Although the induced sensation was often paresthesia, the location corresponded to parts of the innervation regions of the median and ulnar nerves, and electroencephalographic (EEG) recordings confirmed the presence of appropriate responses in relevant cortical areas. Using these sensations as feedback during bidirectional prosthesis control, the patients were able to perform several functional tasks that would not be possible otherwise, such as applying one of three levels of force on an external sensor. Performance during these tasks was high, suggesting that this approach could be a viable alternative to the more invasive solutions, offering a trade-off between the quality of the sensation, and the invasiveness of the intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.