ArticleScientific reports2017
Dissection of iron signaling and iron accumulation by overexpression of subgroup Ib bHLH039 protein.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Ethylene signalling enhances mitochondrial stress tolerance independently of the transcription factor ANAC017 in Arabidopsis.Journal of experimental botany · 2026Article
- Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana.Journal of experimental botany · 2025Article
- Shedding light on iron nutrition: exploring intersections of transcription factor cascades in light and iron deficiency signaling.Journal of experimental botany · 2025Review
- ANAC044 orchestrates mitochondrial stress signaling to trigger iron-induced stem cell death in root meristems.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Quantitative tools for analyzing rhizosphere pH dynamics: localized and integrated approaches.Biology methods & protocols · 2025Article
- Micronutrient deficiency-induced oxidative stress in plants.Plant cell reports · 2024Review
- A CYBDOM protein impacts iron homeostasis and primary root growth under phosphate deficiency in Arabidopsis.Nature communications · 2024Article
- Hordeum vulgare differentiates its response to beneficial bacteria.BMC plant biology · 2023Article
- Understanding the Mechanisms of Fe Deficiency in the Rhizosphere to Promote Plant Resilience.Plants (Basel, Switzerland) · 2023Review
- SEC14-GOLD protein PATELLIN2 binds IRON-REGULATED TRANSPORTER1 linking root iron uptake to vitamin E.Plant physiology · 2023Article
- Iron uptake, signaling, and sensing in plants.Plant communications · 2022Review
- Article
- Transcriptome Analysis Revealed the Molecular Response Mechanism of Non-heading Chinese Cabbage to Iron Deficiency Stress.Frontiers in plant science · 2022Article
- Strategies and Bottlenecks in Hexaploid Wheat to Mobilize Soil Iron to Grains.Frontiers in plant science · 2022Review
- Long-term acclimation to cadmium exposure reveals extensive phenotypic plasticity in Chlamydomonas.Plant physiology · 2021Article
- Reactive oxygen species coordinate the transcriptional responses to iron availability in Arabidopsis.Journal of experimental botany · 2021Article
- All together now: regulation of the iron deficiency response.Journal of experimental botany · 2021Review
- Transcriptomics Reveals Fast Changes in Salicylate and Jasmonate Signaling Pathways in Shoots of Carbonate-TolerantInternational journal of molecular sciences · 2021Article
- Chelators of iron and their role in plant's iron management.Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Review
- Optogenetic control of gene expression in plants in the presence of ambient white light.Nature methods · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is an essential growth determinant for plants, and plants acquire this micronutrient in amounts they need in their environment. Plants can increase iron uptake in response to a regulatory transcription factor cascade. Arabidopsis thaliana serves as model plant to identify and characterize iron regulation genes. Here, we show that overexpression of subgroup Ib bHLH transcription factor bHLH039 (39Ox) caused constitutive iron acquisition responses, which resulted in enhanced iron contents in leaves and seeds. Transcriptome analysis demonstrated that 39Ox plants displayed simultaneously gene expression patterns characteristic of iron deficiency and iron stress signaling. Thereby, we could dissect iron deficiency response regulation. The transcription factor FIT, which is required to regulate iron uptake, was essential for the 39Ox phenotype. We provide evidence that subgroup Ib transcription factors are involved in FIT transcriptional regulation. Our findings pose interesting questions to the feedback control of iron homeostasis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.