ArticleScientific reports2017
Automated video-mosaicking approach for confocal microscopic imaging in vivo: an approach to address challenges in imaging living tissue and extend field of view.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 41 citations in OpenAlex.
- Multiplexed video hyperspectral microendoscopy reveals tumor-immune dynamics in vivo.Research square · 2026Article
- Image stitching for probe-based confocal laser endomicroscopy via a motion consistency constraint.Biomedical optics express · 2026Article
- Rolling shutter-resistant confocal endomicroscopy image stitching via dual-path Gaussian U-Net.Journal of biomedical optics · 2025Article
- Motion-tolerant 3D volumetric multimodality microscopy imaging of human skin with subcellular resolution and extended field-of-view.Communications biology · 2025Article
- Confocal Microscopy for Diagnosis and Management of Cutaneous Malignancies: Clinical Impacts and Innovation.Diagnostics (Basel, Switzerland) · 2023Review
- Skin Cancer Pathobiology at a Glance: A Focus on Imaging Techniques and Their Potential for Improved Diagnosis and Surveillance in Clinical Cohorts.International journal of molecular sciences · 2023Review
- Water-based acrylic marker for reflectance confocal microscopy lesion delineation.Lasers in surgery and medicine · 2022Article
- Challenges for New Adopters in Pre-Surgical Margin Assessment by Handheld Reflectance Confocal Microscope of Basal Cell Carcinoma; A Prospective Single-center Study.Dermatology practical & conceptual · 2022Review
- Intensity-Mosaic: automatic panorama mosaicking of disordered images with insufficient features.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- Real-Time Nonrigid Mosaicking of Laparoscopy Images.IEEE transactions on medical imaging · 2021Article
- TEM image restoration from fast image streams.PloS one · 2021Article
- Diagnostic accuracy of reflectance confocal microscopy for pigmented skin lesions presenting dermoscopic features of cutaneous melanoma.Postepy dermatologii i alergologii · 2020Article
- Real-time video mosaicking to guide handheld in vivo microscopy.Journal of biophotonics · 2020Article
- Software-Based Phase Control, Video-Rate Imaging, and Real-Time Mosaicing With a Lissajous-Scanned Confocal Microscope.IEEE transactions on medical imaging · 2020Article
- Multichannel correlation improves the noise tolerance of real-time hyperspectral microimage mosaicking.Journal of biomedical optics · 2019Article
- Feasibility of a Video-Mosaicking Approach to Extend the Field-of-View For Reflectance Confocal Microscopy in the Oral Cavity In Vivo.Lasers in surgery and medicine · 2019Article
- Peri-operative delineation of non-melanoma skin cancer margins in vivo with handheld reflectance confocal microscopy and video-mosaicking.Journal of the European Academy of Dermatology and Venereology : JEADV · 2019Article
- Label-free in vivo pathology of human epithelia with a high-speed handheld dual-axis confocal microscope.Journal of biomedical optics · 2019Article
- Toward Quantitative Neurosurgical Guidance With High-Resolution Microscopy of 5-Aminolevulinic Acid-Induced Protoporphyrin IX.Frontiers in oncology · 2019Article
- High-resolution microscopy for imaging cancer pathobiology.Current pathobiology reports · 2019Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
We describe a computer vision-based mosaicking method for in vivo videos of reflectance confocal microscopy (RCM). RCM is a microscopic imaging technique, which enables the users to rapidly examine tissue in vivo. Providing resolution at cellular-level morphology, RCM imaging combined with mosaicking has shown to be highly sensitive and specific for non-invasively guiding skin cancer diagnosis. However, current RCM mosaicking techniques with existing microscopes have been limited to two-dimensional sequences of individual still images, acquired in a highly controlled manner, and along a specific predefined raster path, covering a limited area. The recent advent of smaller handheld microscopes is enabling acquisition of videos, acquired in a relatively uncontrolled manner and along an ad-hoc arbitrarily free-form, non-rastered path. Mosaicking of video-images (video-mosaicking) is necessary to display large areas of tissue. Our video-mosaicking methods addresses this need. The method can handle unique challenges encountered during video capture such as motion blur artifacts due to rapid motion of the microscope over the imaged area, warping in frames due to changes in contact angle and varying resolution with depth. We present test examples of video-mosaics of melanoma and non-melanoma skin cancers, to demonstrate potential clinical utility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.